Results 181 to 190 of about 201,939 (380)

The Formation of Guanosine-Nucleotide . Elongation-Factor-G . Ribosome Complexes on Free 70-S Ribosomes, 50-S Subunits, and Polysomes. A Comparative Study [PDF]

, 1977
María J. San-Millán, David VAZQUEZ, Juan Modolell   +2 more
openalex   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Synthesis, H2S releasing properties, antiviral and antioxidant activities and acute cardiac effects of nucleoside 5′-dithioacetates

Scientific Reports
Hydrogen sulfide (H2S) is an endogenous gasotransmitter with cardioprotective and antiviral effects. In this work, new cysteine-selective nucleoside-H2S-donor hybrid molecules were prepared by conjugating nucleoside biomolecules with a thiol-activatable ...
Miklós Bege, Miklós Lovas, Dániel Priksz, Brigitta Bernát, Ilona Bereczki, Rasha Ghanem Kattoub, Richárd Kajtár, Simon Eskeif, Levente Novák, Jan Hodek, Jan Weber, Pál Herczegh, István Lekli, Anikó Borbás   +13 more
doaj   +1 more source

Early‐Onset Movement Disorder Syndrome Caused by Biallelic Variants in PDE1B Encoding Phosphodiesterase 1B

Movement Disorders, EarlyView.
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg, Noam Hadar, Eyal Kristal, Nicola Y. Roberts, Vadim Dolgin, Ilana Aminov, Amit Safran, Nadav Agam, Matan Jean, Ofek Freund, Eamonn G. Sheridan, James A. Poulter, Michelle L. Thompson, Yusra Algoos, Salma Al‐Qahtani, Lama AlAbdi, Sateesh Maddirevula, Verity Hartill, Henry Houlden, Reza Maroofian, Amit Nahum, Ohad S. Birk   +21 more
wiley   +1 more source

The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes.

, 1967
Takehiro Ohta, Souvarish Sarkar, Robert E. Thach   +2 more
openalex   +1 more source

The polyamino‐isoprenyl enhancer NV716 enables the antibacterial activity of two families of multi‐target inhibitors against the ESKAPEE bacterium Enterobacter cloacae

mLife, EarlyView.
Abstract Gram‐negative bacteria are particularly prone to developing antimicrobial resistance (AMR), as evidenced by the WHO's ESKAPEE list of high‐priority pathogens. One strategy that has increased is the use of antibiotic enhancers, which can re‐empower abandoned or poorly active antibiotics against the resistant strain of interest.
Emma Forest, Jordan Lehoux, Alexandre Guy, Thierry Durand, Stéphane Audebert, Luc Camoin, Christopher D. Spilling, Céline Crauste, Stéphane Canaan, Jean Michel Brunel, Jean‐Michel Bolla, Jean‐François Cavalier   +11 more
wiley   +1 more source

The Inhibition of Succinoadenylate Kinosynthetase of Escherichia coli by Adenosine and Guanosine 5'-Monophosphates

, 1963
James Β. Wyngaarden, Roy A. Greenland
openalex   +1 more source

Free 3′‐OH Group of the Terminal Adenosine of the tRNA Molecule Is Essential for the Synthesis in vitro of Guanosine Tetraphosphate and Pentaphosphate in a Ribosomal System from Escherichia coli [PDF]

, 1976
Mathias Sprinzl, Dietmar Richter
openalex   +1 more source

Differential Effects of Wild Blueberry (Poly)Phenol Metabolites in Modulating Lipid Metabolism and Oxidative Stress in 3T3‐L1 Adipocytes

Molecular Nutrition &Food Research, EarlyView.
Metabolites derived from wild blueberry (poly)phenols, such as syringic (SA), vanillic (VA), and isoferulic acids (IA), can modulate lipid metabolism and oxidative stress markers in mature 3T3‐L1 adipocytes treated with free fatty acids (FFAs; oleic/palmitic acid, 750 µM, 2:1 ratio).
Samuele Venturi, Marco Rendine, Mirko Marino, Dorothy Klimis‐Zacas, Patrizia Riso, Cristian Del Bo'   +5 more
wiley   +1 more source

THE ENZYMATIC SYNTHESIS OF GUANOSINE DIPHOSPHATE COLITOSE BY A MUTANT STRAIN OF ESCHERICHIA COLI

, 1962
Edward C. Heath, Alan D. Elbein
openalex   +1 more source