Food Frontiers, EarlyView.Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli +8 more
wiley +1 more source
Naphthyridine carbamate dimer ligand induces formation of Z-RNA-like fold of disease-related RNA and exhibits a molecular glue characteristics in crystal lattice formation. [PDF]
Nucleic Acids ResMateja-Pluta M +4 more
europepmc +1 more source
Ligand specificity and adaptability revealed by the first Guanine-II riboswitch tertiary structure. [PDF]
Nucleic Acids ResLi H +6 more
europepmc +1 more source
Studies of Nucleosides and Nucleotides. XXX. Syntheses of 8-Substitute Guanosine Derivatives
, 1966 Morio Ikehara, Kei Muneyama
openalex +2 more sources
The mechanisms in glucose metabolism of aging hippocampus
Ibrain, EarlyView.Cognitive decline in elders stems from the irreversible loss and functional decline of neurons, with the hippocampus being particularly susceptible to age‐related neuronal deterioration. Glucose acts as the primary fuel for the brain, and a constant provision of glucose to the hippocampus is essential for memory and cognitive functions.
Rui He +6 more
wiley +1 more source
The intrinsic preference of guanosine bases for cleavage-facilitating interactions with phosphodiester moieties in RNA anions revealed by base modifications and mass spectrometry. [PDF]
Nucleic Acids ResPloner A +5 more
europepmc +1 more source
Studies on the Guanosine Degrading System in Bacteria Part I
, 1969 Yasunari Ishida +4 more
openalex +2 more sources
The Guanosine 3′,5′‐Bis(diphosphate) (ppGpp) Cycle [PDF]
, 1979 Dietmar Richter +2 more
openalex +1 more source
Anti-aging effects of guanosine in glial cells
Purinergic Signalling Purinergic Signalling, 2016 D. G. Souza +4 more
semanticscholar +1 more source
In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters
The Journal of Clinical Pharmacology, EarlyView.Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou +9 more
wiley +1 more source