In vitro quality of whole blood-derived red cell concentrates collected, processed and stored in a blood bag set plasticized with di (2-ethylhexyl) terephthalate. [PDF]
Stephenson T +7 more
europepmc +1 more source
Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis +9 more
wiley +1 more source
Metabolic reprogramming by pseudorabies virus: nucleotide metabolism as a central vulnerability for viral replication and pathogenesis. [PDF]
Chen X, Wang Q, Chen X.
europepmc +1 more source
The bacterial dynamin‐like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane association is essential for its protective function, likely preventing explosive membrane rupture following phage infection.
Samia Shafqat +2 more
wiley +1 more source
Guanine Crystal Formation at Physiological pH. [PDF]
Tah Roy B +8 more
europepmc +1 more source
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen +7 more
wiley +1 more source
A disubstituted aniline probe for enhanced peroxidase-based proximal protein labelling. [PDF]
Kaewsapsak P +15 more
europepmc +1 more source
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson +5 more
wiley +1 more source
Post-Column Guanosine Addition as a Screening Tool in the Search for Effective G-Quadruplex Binders-A Case Study of <i>Achyrocline satureioides</i> Phenolic Compounds. [PDF]
Stężycka O +5 more
europepmc +1 more source
Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang +5 more
wiley +1 more source

