Results 281 to 290 of about 225,684 (400)

Gliopreventive effects of guanosine against glucose deprivation in vitro

Purinergic Signalling Purinergic Signalling, 2013
André Quincozes-Santos, L. Bobermin, D. G. Souza, Bruna Bellaver, C. Gonçalves, D. O. Souza   +5 more
semanticscholar   +1 more source

Therapeutic potential of hesperidin in diabetes mellitus‐induced erectile dysfunction through Nrf2‐mediated ferroptosis and oxidative stress

Andrology, EarlyView.
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked to the induction of both ferroptosis and oxidative stress ...
Sheng Xin, Wen Song, Jiaquan Mao, Peng Hu, Zhong Chen, Jihong Liu, Xiaodong Song, Qian Fang, Kai Cui   +8 more
wiley   +1 more source

Synthesis of a Pseudocytidine Nucleoside to Form a Stable and Selective Base Pair with Iso-guanosine in RNA. [PDF]

Org Lett
Miyahara R, Taniguchi Y.
europepmc   +1 more source

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

Andrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu, Kang Liu, Bo Wen, Peng Hu, Taotao Sun, Beining Li, Manan Sulaiman, Shujun Jiang, Tao Wang, Jihong Liu, Yang Luan   +10 more
wiley   +1 more source

Molecular insights into de novo small-molecule recognition by an intron RNA structure. [PDF]

Proc Natl Acad Sci U S A
Liu T, Xu L, Chung K, Sisto LJ, Hwang J, Zhang C, Van Zandt MC, Pyle AM.   +7 more
europepmc   +1 more source

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

, 1976
Chhabirani Mukherjee, Robert J. Lefkowitz   +1 more
openalex   +1 more source

Cyclic guanosine monophosphate as a mediator of vasodilation.

Journal of Clinical Investigation, 1986
F. Murad
semanticscholar   +1 more source

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

Andrology, EarlyView.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu, Suping Niu, Fan Huang, Lu Jin, Qun Gu, Yanting Li, Chongyou Lee, Zhenwei Xie, Xiangxing Liu, Fang Men, Wenyan Zhao, Shuang Li, Yian Liu, Qian Wang, Huaying Fan, Jiaojiao Zhang, Shuangshuang Lin, Liming Chen, Yi Fang   +18 more
wiley   +1 more source

Demonstration of a Heat-Stable Cyclic GMP Phosphodiesterase in the Medium of Physarum flavicomum [PDF]

, 1985
Lynch, Thomas J., Ross, Mark S.
core   +2 more sources

Comparative efficacy of combination therapy including regenerative therapies versus monotherapy for erectile dysfunction: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background and objective The Current European Association of Urology guidelines do not provide recommendation for combination of regenerative therapies with standard therapies for erectile dysfunction. The aim of this study was to compare the efficacy of combined regenerative therapy with monotherapy for erectile dysfunction.
Alberto Quistini, Giuseppe Fallara, Marco Tozzi, Massimiliano Depalma, Rocco Damiano, Alessandro Palmieri, Fabio Castiglione, Andrea Salonia, Roberto Bianchi, Matteo Ferro, Asif Muneer, Hussain M. Alnajjar, Karl H. Pang   +12 more
wiley   +1 more source