Results 281 to 290 of about 201,939 (380)

European Guideline (EuroGuiDerm) on atopic eczema: Living update

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg, M. Kinberger, B. Arents, N. Aszodi, S. Barbarot, T. Bieber, H. A. Brough, P. Calzavara‐Pinton, S. Christen‐Zaech, M. Deleuran, M. Dittmann, N. Fosse, K. Gáspár, L. A. A. Gerbens, U. Gieler, G. Girolomoni, S. Gregoriou, S. Holland, C. G. Mortz, A. Nast, U. Nygaard, E. M. Rehbinder, J. Ring, M. Rossi, E. Serra‐Baldrich, D. Simon, Z. Z. Szalai, J. C. Szepietowski, A. Torrelo, T. Werfel, R. N. Werner, C. Flohr   +31 more
wiley   +1 more source

Synergistic Antibacterial Action of Norfloxacin-Encapsulated G4 Hydrogels: The Role of Boronic Acid and Cyclodextrin. [PDF]

Gels
Sardaru MC, Rosca I, Morariu S, Ursu EL, Rotaru A.   +4 more
europepmc   +1 more source

SGLT‐2 inhibitors for cardiac amyloidosis: Hype or hope?

European Journal of Clinical Investigation, EarlyView.
Flavio Tangianu, Eleonora Nicolini, Francesco Dentali, Aldo Bonaventura   +3 more
wiley   +1 more source

Late blight pathogen targets host Rab‐G3 GTPases with an atypical GTPase‐activating protein

Journal of Integrative Plant Biology, EarlyView.
The Phytophthora infestans RXLR effector Pi17063 functions as an atypical GTPase‐activating protein of host positive immune regulators, specifically the small GTPase NbRab‐G3. Pi17063 promotes the relocalization of NbRab‐G3 proteins to the cytoplasm, where they are inactive, disrupting the balance of the NbRab‐G3 switch and thus leading to enhanced ...
Song Liu, Liwen Ding, Xiong Liu, Xiaoxi Xing, Jinyang Li, Tiantian Yan, Yuli Huang, Yuan Liu, Yisa Wang, Xia Zhang, Zeming Liu, Xiyu Cao, Yuling Meng, Weixing Shan   +13 more
wiley   +1 more source

Correction: Schaltz et al. A Theoretical Study of Hydrogen Abstraction Reactions in Guanosine and Uridine. Int. J. Mol. Sci. 2023, 24, 8192. [PDF]

Int J Mol Sci
Schaltz KF, Sauer SPA.
europepmc   +1 more source

Phosphorylation of cardiac troponin by guanosine 3‘:5‘-monophosphate-dependent protein kinase.

, 1978
Donald Blumenthal, James T. Stull, Gordon N. Gill   +2 more
openalex   +1 more source

Residual guanosine 3',5'-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations.

Journal of Biological Chemistry, 1991
Hua-Qing Xiao, M. Kálmán, Kenji Ikehara, S. Zemel, G. Glaser, M. Cashel   +5 more
semanticscholar   +1 more source

Genomic footprinting reveals cell-type-specific binding of ubiquitous transcription factors [PDF]

, 1987
Becker, Peter B., Ruppert, Siegfried, Schütz, Günther   +2 more
core  

Xanthine Derivative KMUP‐3 Alleviates Periodontal Bone Resorption by Inhibiting Osteoclastogenesis and Macrophage Pyroptosis

Journal of Periodontal Research, EarlyView.
This study reveals that our self‐developed xanthine derivative, KMUP‐3, suppresses osteoclastogenesis, inflammation, and pyroptosis by inhibiting the NLRP3 inflammasome. It also alleviates periodontal bone loss in periodontitis rats, highlighting its potential as a novel therapeutic option for periodontitis.
Shang‐En Huang, Kai‐Fang Hu, Meng‐Xuan Lin, Ching‐Jiunn Tseng, Bin‐Nan Wu, Zen‐Kong Dai, Jong‐Hau Hsu, Jwu‐Lai Yeh   +7 more
wiley   +1 more source

Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition. [PDF]

Nat Commun
Shi X, Li M, Liu Z, Tiessen J, Li Y, Zhou J, Zhu Y, Mahesula S, Ding Q, Tan L, Feng M, Kageyama Y, Hara Y, Tao JJ, Luo X, Patras KA, Lorenzi PL, Huang S, Stevens AM, Takahashi K, Issa GC, Samee MAH, Agathocleous M, Nakada D.   +23 more
europepmc   +1 more source