Results 311 to 320 of about 225,684 (400)

Spectrofluorimetric determination of cyclic guanosine monophosphate in human nasal secretions: evaluating levels in healthy individuals and patients with olfactory dysfunction. [PDF]

BMC Chem
Abdelazim MH, Alsenani F, Alharbi A, Baali FH, Baali AH, Abduljabbar MH, Alnemari RM, Algarni MA.   +7 more
europepmc   +1 more source

Determination and quantification of cyclic guanosine- and cyclic adenosine monophosphate (cGMP and cAMP) in human plasma and animal tissues by HILIC SPE in combination with LC-MS/MS [PDF]

, 2012
Lynen, Frederic, Sandra, Patrick, Van Damme, Thomas, Zhang, Yanhua   +3 more
core  

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

The FEBS Journal, EarlyView.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone, Linley R. Schofield, Patrick J. B. Edwards, Andrew J. Sutherland‐Smith, Ron S. Ronimus   +4 more
wiley   +1 more source

New alternatives in photoprotection: Preparation and evaluation of lamellar silicate derivatives and their use as sunscreens

International Journal of Cosmetic Science, EarlyView.
The use of nanotechnology in sunscreens has increased, with various filters and organoclays tested for new intercalated formulations. As animal toxicity tests decrease, New Approach Methodologies are favoured. The S4 + OMC‐NC improved cell survival under SSL and showed antimutagenic properties, making it a promising candidate for safe photoprotection ...
Daniel Mabundu Kibwila, Alice Simon, Letícia Coli Louvisse de Abreu, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Marcelo de Pádula, Lucio Mendes Cabral   +6 more
wiley   +1 more source

Purine nucleoside phosphorylase dominates Influenza A virus replication and host hyperinflammation through purine salvage. [PDF]

Signal Transduct Target Ther
Yue Y, Li Q, Chen C, Yang J, Song W, Zhou C, Cui Y, Wei Z, He Q, Wang C, Lin H, Li J, Li J, Xi J, Song X, Yang W, Zhang Z, Shu W, Guo L, Wang S.   +19 more
europepmc   +1 more source

Recovery From Anorexia Nervosa: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Loss-of-function coding variants in the Ras of complex proteins/GTPase domain of leucine rich repeat kinase 2. [PDF]

Protein Sci
Butterfield S, Herbst S, Lewis PA.
europepmc   +1 more source

Periodontitis and Platelets Status: A Systematic Review With Meta‐Analysis and Trial Sequential Analysis

Journal of Periodontal Research, EarlyView.
The certainty is moderate for a slightly higher platelet count in patients with periodontitis compared to individuals without periodontitis and low for no difference in mean platelet volume between the two groups. The evidence is not robust to claim a clear difference in other platelet activation biomarkers between the two groups.
Dimitris Sokos, Marja L. Laine, Elena A. Nicu, Kelly Hiu Lam Chung, Ni‐ni Dong Qing Sluijk, Dagmar Else Slot, Sergio Bizzarro   +6 more
wiley   +1 more source