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Tautomerism and Protonation of Guanosine [PDF]

Science, 1963
Guanosine has been demonstrated, by infrared and nuclear magnetic resonance spectroscopy, to have a keto-amino structure in neutral aqueous solution and to undergo protonation at N 7 in acid solution.
H. Todd Miles, Joe Frazier, Frank B. Howard   +2 more
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Conformation of acetylaminofluorene and aminofluorene modified guanosine and guanosine derivatives

Biochemical and Biophysical Research Communications, 1980
Abstract Acetylaminofluorene and aminofluorene modified Guo, GMP, d(GpA) and d(ApG) have been studied by circular dichroism and 1H nuclear magnetic resonance. Aminofluorene modified Guo is preferentially in the anti conformation and acetylaminofluorene modified Guo in the syn conformation.
P. Rio, Marc Leng, M. Ptak
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Novel Guanosine Derivatives as Anti-HCV NS5b Polymerase: A QSAR and Molecular Docking Study.

Medicinal chemistry, 2019
BACKGROUND IDX-184 is a guanosine derivative having a potent inhibitory performance against HCV NS5b polymerase. OBJECTIVE To test three different groups of 2'C - modified analogues of guanosine nucleotide against HCV polymerase.
Abdo A. Elfiky
semanticscholar   +1 more source

Scalene Waveform for Codetection of Guanosine and Adenosine Using Fast-Scan Cyclic Voltammetry.

Analytical Chemistry, 2019
Guanosine and adenosine are important neuromodulators in the brain and work in cooperation to mitigate the effects of stroke, traumatic injury, and other neurological events.
Michael T. Cryan, Ashley E. Ross
semanticscholar   +1 more source

Penicillin interaction with guanosine

Biochemical and Biophysical Research Communications, 1972
Abstract Because of the widespread use of penicillins as antibacterial agents, the question of how penicillin affects the function and structure of nucleic acids becomes of biological importance. This communication reports a nuclear magnetic resonance study which shows that penicillin-G interacts with guanosine in dimethyl sulfoxide and can break the
San Kao, Norman C. Li, Lou S. Kan, Frank K. Schweighardt   +3 more
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UV‐Light‐Induced Hydrogen Transfer in Guanosine–Guanosine Aggregates

Chemistry – A European Journal, 2013
AbstractAggregates of a lipophilic guanine (G) derivative have been studied in n‐hexane by femtosecond‐to‐microsecond UV‐visible broadband transient absorption, stationary infrared and UV‐visible spectroscopy and by quantum chemical calculations. We report the first time‐resolved spectroscopic detection of hydrogen transfer in GG aggregates, which ...
Hunger Katharina, Buschhaus Laura, Biemann Lars, Braun Michaela, Kovalenko Sergey, Improta Roberto, Kleinermanns Karl   +6 more
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ChemInform Abstract: Condensation of Triformylmethane with Guanosine.

ChemInform, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Niangoran Koissi, Leif Kronberg, Kari Neuvonen, Tony Munter, Harri Lönnberg   +4 more
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Subsecond detection of guanosine using fast-scan cyclic voltammetry.

In Analysis, 2018
Guanosine is an important neuromodulator and neuroprotector in the brain and is involved in many pathological conditions, including ischemia and neuroinflammation.
Michael T. Cryan, Ashley E. Ross
semanticscholar   +1 more source

Oxidation potentials of guanine, guanosine and guanosine-5′-monophosphate: Theory and experiment

Electrochimica Acta, 2019
Abstract Guanine, having lower one-electron oxidation potential than other nucleobases, is of relevance to oxidative degradation of nucleic acids in mutagenesis, carcinogenesis, and aging. Here we compare oxidation potentials of guanine (G), guanosine (Guo), deoxyguanosine (dGuo), guanosine -5′- monophosphate (GMP) and 2′- deoxyguanosine -5 ...
Liška, A. (Alan), Třísková, I., Ludvík, J. (Jiří), Trnková, L.   +3 more
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Reactions of formaldehyde with guanosine

Toxicology Letters, 1981
Formaldehyde reacted with guanosine and the products were assayed using fluorescence spectroscopy at different pHs. The reaction products were fluorescent in alkali only as was found with commercial N-2 methylguanosine. Thus, formaldehyde appeared to react with N-2 of guanosine. The reaction was completed with 30s both at 0 degrees C or at 21 degrees C.
openaire   +3 more sources