Results 141 to 150 of about 118,645 (287)

Non-canonical Gq activation by orexin receptor type 2 and lemborexant observed in microsecond molecular dynamics simulations

Scientific Reports
Orexins are hypothalamic neuropeptides primarily involved in regulating the sleep/wakefulness cycle and circadian rhythm. They bind to the orexin receptor type 1 (OX1) and type 2 (OX2), well-known drug targets in the treatment of sleep disorders, that ...
Paulina Dragan, Valerie Gratio, Thierry Voisin, Alain Couvineau, Dorota Latek   +4 more
doaj   +1 more source

Changes in the Concentrations of Guanosine 5′-Diphosphate 3′-Diphosphate and the Initiating Nucleoside Triphosphate Account for Inhibition of rRNA Transcription in Fructose-1,6-Diphosphate Aldolase ( fda ) Mutants

, 2003
David A. Schneider, Richard L. Gourse
openalex   +1 more source

Concentration and synthesis of phosphoribosylpyrophosphate in erythrocytes from normal, hyperuricemic, and gouty subjects. [PDF]

, 1971
Phosphoribosylpyrophosphate (PRPP) synthetase activity and the intracellular concentration of PRPP were assayed in erythrocytes from patients with primary hyperuricemia and primary metabolic gout.
Meyskens, FL, Williams, HE
core  

Association of NGF receptors with membrane rafts in PC12 cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 2001
Nerve Growth Factor (NGF) signal transduction is involved in the survival, differentiation and maintenance of neurons through the receptors TrkA and p75NTR. These receptors activate downstream protein kinase cascades that regulate cell survival.
Clements, Shona Marie
core  

Oncogenic mutant KRAS inhibition through oxidation at cysteine 118

Molecular Oncology
Specific reactive oxygen species activate the GTPase Kirsten rat sarcoma virus (KRAS) by reacting with cysteine 118 (C118), leading to an electron transfer between C118 and nucleoside guanosine diphosphate (GDP), which causes the release of GDP. Here, we
Maximilian Kramer‐Drauberg, Ettore Petrini, Alessia Mira, Enrico Patrucco, Rossella Scardaci, Ilenia Savinelli, Haiyun Wang, Keying Qiao, Giovanna Carrà, Marie‐Julie Nokin, Zhiwei Zhou, Kenneth D. Westover, David Santamaria, Paolo E. Porporato, Chiara Ambrogio   +14 more
doaj   +1 more source

THE ENZYMATIC SYNTHESIS OF GUANOSINE DIPHOSPHATE COLITOSE BY A MUTANT STRAIN OF ESCHERICHIA COLI

, 1962
Edward C. Heath, Alan D. Elbein
openalex   +2 more sources

Identification of guanosine diphosphate derivatives of d-xylose, d-glucose and d-galactose in mature strawberry leaves [PDF]

, 1967
Robert R. Selvendran, F. A. Isherwood
openalex   +1 more source

Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X‐ray crystallography.

EMBO Journal, 1985
T. Cour, J. Nyborg, S. Thirup, B. Clark
semanticscholar   +1 more source

Synthesis of Guanosine 5'-Diphosphate, 2'- (or 3'-) Diphosphate and Related Nucleotides in a Variety of Physiological Conditions

, 1971
Gordon Edlin, Pierluigi Donini
openalex   +1 more source

Trehalose Phosphate Synthesis in Streptomyces hygroscopicus: Purification of Guanosine Diphosphate d-Glucose: d-Glucose-6-Phosphate 1-Glucosyl-Transferase

Journal of Bacteriology, 1968
A. Elbein
semanticscholar   +1 more source