Results 161 to 170 of about 144,757 (372)

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

Andrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu, Kang Liu, Bo Wen, Peng Hu, Taotao Sun, Beining Li, Manan Sulaiman, Shujun Jiang, Tao Wang, Jihong Liu, Yang Luan   +10 more
wiley   +1 more source

Effects of cyclic nucleotides on midgut infections and maturation of T. b. brucei in G. m. morsitans

Parasites & Vectors, 2008
Cyclic nucleotide signalling through cyclic adenosine monophosphate (cAMP) is thought to play an important role in the transformation of the long slender (dividing) form to the short-stumpy (arrested) form in the mammalian bloodstream but the role of ...
Maudlin Ian, MacLeod Ewan T, Welburn Susan C   +2 more
doaj   +1 more source

Thesis: The Effects of Hypoxia, Metabolic Restriction and Magnetic Fields on Chromosome Instability and Karyotype Contraction in Cancer Cell Lines [PDF]

arXiv, 2014
Background: Biological effects of extra-low-frequency (ELF) magnetic fields (MFs) have lacked a credible mechanism of interaction between MFs and living material. Objectives: To examine the effect of ELF-MFs on cancer cells. Methods: Five cancer cell lines were exposed to ELF-MFs within the range of 0.025-5 microTesla, and the cells were examined for ...
arxiv  

Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age

Acta Paediatrica, EarlyView.
ABSTRACT Aim Pulmonary hypertension is frequent in neonates with a congenital diaphragmatic hernia, but long‐term data have been scarce. Our aim was to examine its prevalence, evolution and management and identify factors associated with its persistence.
Alice Dirickx, Marilyne Levy, Kelly Mellul, Maxime Coignard, Naziha Khen‐Dunlop, Alexandre Lapillonne, Julien Stirnemann, Elsa Kermorvant‐Duchemin   +7 more
wiley   +1 more source

Regulation of the physiology and virulence of Ralstonia solanacearum by the second messenger 2',3'-cyclic guanosine monophosphate. [PDF]

Nat Commun, 2023
Li X, Yin W, Lin JD, Zhang Y, Guo Q, Wang G, Chen X, Cui B, Wang M, Chen M, Li P, He YW, Qian W, Luo H, Zhang LH, Liu XW, Song S, Deng Y.   +17 more
europepmc   +1 more source

Papaverine safety during pregnancy: Insights from a large population‐based cohort of pregnancies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Papaverine hydrochloride functions as an antispasmodic and vasodilator medication. Data concerning the teratogenic risk of papaverine is currently lacking. The aims of this paper are to examine the association between first‐trimester exposure to papaverine and major congenital malformations and the association between third trimester ...
Yael Levi, Tal Michael, Saar Dor, Gali Pariente, Eitan Lunenfeld, Amalia Levy, Shira Birenstock‐Choen, Sharon Daniel   +7 more
wiley   +1 more source

Salvage enzymes in nucleotide biosynthesis [PDF]

, 2007
Balanced pools of deoxyribonucleoside triphosphates (dNTPs), the building blocks of DNA, and ribonucleoside triphosphates (NTPs), the precursors of RNA, are crucial for a controlled cell proliferation.
Kosinska, Urszula
core  

Cyclic Guanosine Monophosphate Measurement

Definitions, 2020

semanticscholar   +1 more source

Tissue Guanosine-3′,5′-Cyclic Monophosphate Levels and Soluble Guanylate Cyclase Activity [PDF]

, 1978
W. Austin Spruill, Alton L. Steiner, H. Shelton Earp   +2 more
openalex   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source