Results 181 to 190 of about 165,669 (302)

Molecular mechanisms of plant NLR activation and signalling

open access: yesThe Plant Journal, Volume 125, Issue 3, February 2026.
SUMMARY Plants rely on NLRs (nucleotide‐binding leucine‐rich repeat receptors) to recognise effector proteins secreted by pathogens into plant cells and to deliver disease resistance. Plant NLRs are broadly characterised by their N‐terminal domains, which include the TIR (Toll/interleukin‐1 receptor) and the CC (coiled‐coil) domains.
Natsumi Maruta   +3 more
wiley   +1 more source

<i>Geum japonicum</i> Thunb. exhibits anti-platelet activity via the regulation of cyclic guanosine monophosphate. [PDF]

open access: yesFront Pharmacol
Lee YY   +8 more
europepmc   +1 more source

Right ventricular and cyclic guanosine monophosphate signalling abnormalities in stages B and C of heart failure with preserved ejection fraction. [PDF]

open access: yesESC Heart Fail, 2021
Petit T   +13 more
europepmc   +1 more source

Effects of soluble guanylyl cyclase stimulation on muscle oxygenation and exercise capacity in heart failure with mildly reduced ejection fraction

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 474-488, 1 February 2026.
Abstract Heart failure (HF) with a mildly reduced ejection fraction (HFmrEF; 40%–49%) is present in ≤25% of HF patients. Therapeutic treatment options for HFmrEF‐associated exercise intolerance are limited. Nitric oxide (NO)‐independent stimulation of soluble guanylyl cyclase to improve peripheral vasodilatation offers a novel approach to enhance ...
Ramona E. Weber   +10 more
wiley   +1 more source

Cyclic guanosine monophosphate and 10-year change in left ventricular mass: the Multi-Ethnic Study of Atherosclerosis (MESA). [PDF]

open access: yesBiomarkers, 2021
Subramanya V   +13 more
europepmc   +1 more source

hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is essential for oocyte development and female fertility. Oocyte‐specific deletion of Hnrnpu leads to follicular arrest, impaired meiotic maturation, mitochondrial dysfunction, and infertility.
Jinmei Li   +8 more
wiley   +1 more source

Shunxin decoction improves diastolic function in rats with heart failure with preserved ejection fraction induced by abdominal aorta constriction through cyclic guanosine monophosphate-dependent protein kinase Signaling Pathway. [PDF]

open access: yesJ Tradit Chin Med, 2022
Jiaying Z   +14 more
europepmc   +1 more source

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