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Adenosine relaxes vagina smooth muscle through the cyclic guanosine monophosphate- and cyclic guanosine monophosphate-dependent pathways.

The Journal of Sexual Medicine
BACKGROUND In males, adenosine (ADO) is known to relax penile smooth muscles, although its role in the vagina is not yet fully elucidated. AIM This study investigated the effect of ADO on vagina smooth muscle activity, using a validated female Sprague ...
I. Cellai   +11 more
semanticscholar   +3 more sources

Cyclic Guanosine Monophosphate and Cellular Growth

Science, 1975
The addition of serum to nongrowing cells decreases cyclic guanosine monophosphate and cyclic adenosine monophosphate levels and promotes cell growth.
Z, Miller   +3 more
openaire   +2 more sources

PHOTOADDITION OF CHLORPROMAZINE TO GUANOSINE‐5′‐MONOPHOSPHATE

Photochemistry and Photobiology, 1986
Abstrart—The photochemistry of chlorpromazine (CPZ) with guanosine‐5′‐monophosphate (GMP) was studied as a model for the photoaddition of CPZ to DNA. Irradiation of CPZ with calf thymus DNA produced a product emitting at 520 nm, whereas with GMP emission was at 495 nm.
T A, Ciulla, G A, Epling, I E, Kochevar
openaire   +2 more sources

The structure of helical 5′-guanosine monophosphate

Journal of Molecular Biology, 1975
Abstract An X-ray fiber diffraction analysis of 5′-GMP has been carried out. It is concluded on the basis of very well oriented diffraction patterns that the structure consists of a continuously hydrogen-bonded helix with 15 nucleotides in four turns.
V, Sasisekharan   +2 more
openaire   +2 more sources

Chlorine Dioxide Oxidation of Guanosine 5‘-Monophosphate

Chemical Research in Toxicology, 2006
The reactions between aqueous ClO2 and guanosine 5'-monophosphate (5'-GMP) are investigated from pH 5.96 to 8.30. The decay of ClO2 follows mixed first-order and second-order kinetics. The addition of chlorite (0.01-0.05 M) to the reaction mixture suppresses the reaction rate and changes the observed decay of ClO2 to second-order.
Michael J, Napolitano   +2 more
openaire   +2 more sources

Structure of barium guanosine 5'-monophosphate

Acta Crystallographica Section C Crystal Structure Communications, 1992
2Ba 2+ .2C 10 H 10 N 5 O 8 P 2- .12H 2 O cristallise dans P2 1 2 1 2 1 avec a = 21,37, b = 22,04 et c = 8,66 A, Z = 4; affinement jusqu'a R = 0,061. Les guanosine sont empilees en colonnes avec un tunnel d'ions Ba coordines a travers le cristal. Il n'y a pas d'empilement base-base, ni de liaison hydrogene base-base.
M. E. A. Churchill   +2 more
openaire   +1 more source

Guanosine 3′,5′-Monophosphate-Dependent Protein Kinase

1979
Publisher Summary This chapter reviews the information about the structure, function, and regulation of G-kinase. Studies indicate that significant similarities and significant differences exist between G-kinase and A-kinase. A-kinase and G-kinase represent extensively regulated allosteric proteins that function as central mediators in the action of ...
G N, Gill, R W, McCune
openaire   +2 more sources

Oxidation potentials of guanine, guanosine and guanosine-5′-monophosphate: Theory and experiment

Electrochimica Acta, 2019
Abstract Guanine, having lower one-electron oxidation potential than other nucleobases, is of relevance to oxidative degradation of nucleic acids in mutagenesis, carcinogenesis, and aging. Here we compare oxidation potentials of guanine (G), guanosine (Guo), deoxyguanosine (dGuo), guanosine -5′- monophosphate (GMP) and 2′- deoxyguanosine -5 ...
Liška, A. (Alan)   +3 more
openaire   +2 more sources

Cyclic guanosine monophosphate (GMP) levels in ocular tissues

Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie, 1977
The cyclic 3′5′ guanosine monophosphate (cGMP) content of tissues of the rabbit eye was studied. Very high levels of the cyclic nucleotide were detected in the retina and rather high ones in the choroid and vitreous body, while the levels found in the iris, lens, and aqueous humor were many times lower.
L, Bonomi, I, Fregona, L, Tomazzoli
openaire   +2 more sources

Atrial Natriuretic Peptides and Cyclic Guanosine Monophosphate Metabolism

The American Journal of the Medical Sciences, 1995
Atrial natriuretic factor (ANF), consisting of amino acids 99-126 of the 126 amino acid ANF prohormone, increases cyclic guanosine monophosphate (GMP) (thought to be the mediator of its physiologic effects) in plasma and urine of human subjects. Long-acting natriuretic peptide, vessel dilator, and kaliuretic peptide, consisting of amino acid 1-30, 31 ...
D L, Vesely   +5 more
openaire   +2 more sources

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