Results 241 to 250 of about 144,757 (372)

MPYS/STING-Mediated TNF-α, Not Type I IFN, Is Essential for the Mucosal Adjuvant Activity of (3′–5′)-Cyclic-Di-Guanosine-Monophosphate In Vivo

Journal of Immunology, 2014
Steven M Blaauboer, Vincent D. Gabrielle, Lei Jin   +2 more
semanticscholar   +1 more source

A Fourier transform infrared study of the electrophilic attack at the N₇-site of guanosine-5′-monophosphate [PDF]

, 1984
H.A. Tajmir‐Riahi, T. Théophanides
openalex   +1 more source

A Robust Strategy for Introducing Amino‐Modifiers in Nucleic Acids: Enabling Novel Amino Tandem Oligonucleotide Synthesis in DNA and RNA

Chemistry – A European Journal, Volume 31, Issue 26, May 8, 2025.
We report a simple, efficient, and cost‐effective methodology for introducing amino‐modifiers into DNA and RNA using a commercially available solid support. By incorporating a base‐labile sulfonyl linker within the strand, we developed an amino‐containing tandem oligonucleotide synthesis (aTOS) methodology, which enables the introduction of multiple ...
Jagandeep S. Saraya, Nicholas G. Horton, Scott R. Sammons, Derek K. O′Flaherty   +3 more
wiley   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, Volume 12, Issue 17, May 8, 2025.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

Beta Testing New Roles of Cyclic Guanosine Monophosphate in Cardiac Myocyte Contractility. [PDF]

JACC Basic Transl Sci
Blanton RM.
europepmc   +1 more source

Guanosine 3':5'-monophosphate-dependent protein kinase from silkworm, properties of a catalytic fragment obtained by limited proteolysis.

, 1976
Masatoshi Inoue, Akira Kishimoto, Yoshimi Takai, Yasutomi Nishizuka   +3 more
openalex   +1 more source

Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship

Annals of Neurology, Volume 97, Issue 5, Page 809-825, May 2025.
Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.
Ugo Sorrentino, Audrey G. O'Neill, Justin M. Kollman, Hyder A. Jinnah, Michael Zech   +4 more
wiley   +1 more source

Bidirectional regulation of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon gene pathway and its impact on hepatocellular carcinoma. [PDF]

World J Gastrointest Oncol
Nie AY, Xiao ZH, Deng JL, Li N, Hao LY, Li SH, Hu XY.   +6 more
europepmc   +1 more source

A new nucleotide involved in the stringent response in Escherichia coli. Guanosine 5‘-diphosphate-3‘-monophosphate.

, 1979
C C Pao, Jonathan Gallant
openalex   +1 more source

High resolution nuclear magnetic resonance studies of platinum(II) – guanosine-5′-monophosphate interactions in aqueous solutions [PDF]

, 1981
Moschos G. Polissiou, Minh Tan Phan Viet, M. St-Jacques, Théophile Theophanides   +3 more
openalex   +1 more source