Results 41 to 50 of about 144,757 (372)
Gastroprotective effects of oral nucleotide administration [PDF]
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A+4 more
core +2 more sources
Metabolomic response of osteosarcoma cells to nanographene oxide-mediated hyperthermia [PDF]
Nanographene oxide (nGO)-mediated hyperthermia has been increasingly investigated as a localised, minimally invasive anticancer therapeutic approach. Near InfraRed (NIR) light irradiation for inducing hyperthermia is particularly attractive, because biological systems mostly lack chromophores that absorb in this spectral window, facilitating the ...
arxiv +1 more source
Dietary nitrate enhances the contractile properties of human skeletal muscle [PDF]
Dietary nitrate, a source of nitric oxide (NO), improves the contractile properties of human muscle. We present the hypothesis that this is due to nitrosylation of the ryanodine receptor and increased NO signaling via the soluble guanyl cyclase-cyclic ...
Coggan, Andrew R, Peterson, Linda R
core +2 more sources
The hydrolysis of cGMP by phosphodiesterase was conducted in [18O]water to determine the site of bond cleavage and the stoichiometry of 18O incorporation into 5'-GMP. Three different forms of phosphodiesterase including a calmodulin-calcium-dependent enzyme in its basal and activated states were examined. The hydrolysis of cGMP catalyzed by each of the
Timothy F. Walseth+4 more
openaire +3 more sources
Without catalyst! A non‐enzymatic, spontaneous route to the formation of short, mixed‐sequence RNA strands from 2′,3′‐cyclic ribonucleotides is shown. The reaction occurs by drying at the air–water interfaces. Abstract For the emergence of life, the abiotic synthesis of RNA from its monomers is a central step.
Avinash Vicholous Dass+16 more
wiley +1 more source
Dynamics of Microtubule Growth and Catastrophe [PDF]
We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP from the end of a microtubule at rate mu.
arxiv +1 more source
Liberators of NO exert a dual effect on renin secretion from isolated mouse renal juxtaglomerular cells [PDF]
This study aimed to examine the role of nitric oxide (NO) in the regulation of renin secretion from renal juxtaglomerular (JG) cells. Using primary cultures of mouse renal JG cells, we found that sodium nitroprusside (SNP) and 3-morpholino-sydnonimin ...
Kurtz, Armin, Schricker, K.
core +1 more source
Endothelium-derived relaxing factor has been recently identified as nitric oxide. The purpose of this study was to determine if vasodilator drugs that generate nitric oxide inhibit vascular smooth muscle mitogenesis and proliferation in culture.
U. Garg, A. Hassid
semanticscholar +1 more source
Dynamics of Microtubule Instabilities [PDF]
We investigate the dynamics of an idealized model of microtubule growth that evolves by: (i) attachment of guanosine triphosphate (GTP) at rate lambda, (ii) conversion of GTP to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP at rate mu. As a function of these rates, a microtubule can grow steadily or its length can fluctuate wildly.
arxiv +1 more source
Determination of total potentially available nucleosides in bovine milk [PDF]
Bovine colostrum and milk samples were collected from two herds over the course of the first month post-partum, pooled for each herd by stage of lactation and total potentially available nucleosides were determined.
Gill, Brendon D.+2 more
core +2 more sources