Results 191 to 200 of about 84,847 (305)

Autosomal Recessive Guanosine Triphosphate Cyclohydrolase I Deficiency: Redefining the Phenotypic Spectrum and Outcomes. [PDF]

Mov Disord Clin Pract
Novelli M, Tolve M, Quiroz V, Carducci C, Bove R, Ricciardi G, Yang K, Manti F, Pisani F, Ebrahimi-Fakhari D, Galosi S, Leuzzi V.   +11 more
europepmc   +1 more source

Inhibition of luteinizing-hormone exocytosis by guanosine 5′-[γ-thio]triphosphate reveals involvement of a GTP-binding protein distal to second-messenger generation [PDF]

, 1991
P. Anton van der Merwe, Robert P. Millar, I. Wakefield, James S. Davidson   +3 more
openalex   +1 more source

IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational Scope

Cancer Science, Volume 116, Issue 12, Page 3250-3265, December 2025.
This review provides a systematic summary of the current understanding of IMPDH biology, emphasizing its complex regulation and therapeutic relevance in cancer. We will outline key unresolved questions, including isozyme‐specific roles and mechanisms for escaping regulations, and propose mechanistic and translational strategies to design IMPDH‐targeted
Aki Ogawa‐Iio, Koh Takeuchi, Keita Shigemi, Michelle Jane Genoveso, Hiroaki Niitsu, Iemasa Koh, Yusei Ota, Keita Yamane, Takao Hinoi, Natsuki Osaka, Masashi Oshima, Tomohiro Ishikawa, Tomoyuki Mizuno, Manabu Natsumeda, Kensuke Tateishi, Rintaro Hashizume, Satoru Osuka, Susumu Goyama, Tomoharu Yasuda, Toshiya Senda, Atsuo T. Sasaki   +20 more
wiley   +1 more source

Prognostic significance and therapeutic potential of guanosine triphosphate cyclohydrolase 1 in esophageal squamous cell carcinoma: clinical implications of ferroptosis and lipid peroxidation regulation. [PDF]

Front Oncol
Sakano M, Tomita Y, Kanazawa T, Ishibashi S, Ikeda M, Oshita H, Hananoi Y, Kato Y, Yamamoto K, Furukawa A, Kinoshita M, Haruki S, Tokunaga M, Kinugasa Y, Kurata M, Kitagawa M, Ohashi K, Yamamoto K.   +17 more
europepmc   +1 more source

Inhibition of bacteriophage-Q β ribonucleic acid polymerase by guanosine triphosphate analogues [PDF]

, 1979
Robert R. Brooks
openalex   +1 more source

Essential developmental processes in Physcomitrium patens require distinct levels of total activity provided by functionally redundant PpROP GTPases

New Phytologist, Volume 248, Issue 6, Page 2865-2890, December 2025.
Summary RHO (RAS homologous) GTPases regulate important cellular and developmental processes in most eukaryotes. Plant‐specific ROP (RHO of plants) GTPase families expanded and functionally diversified during the evolution of vascular plants, but contain few members in nonvascular extant relatives of early land plants.
Aude Le Bail, Benedikt Kost, Janina Nüssel, Tamara Isabeau Lolis, David Koch, Hildegard Voll, Sylwia Schulmeister, Alexander Kaier, Karin Ljung, Maria Ntefidou   +9 more
wiley   +1 more source

Tubulin sequence region beta 155-174 is involved in binding exchangeable guanosine triphosphate.

, 1987
Juliane Hesse, M Thierauf, Herwig Ponstingl   +2 more
openalex   +1 more source

Evidence that insulin and guanosine triphosphate regulate dephosphorylation of the β-subunit of the insulin receptor in sarcolemma membranes isolated from skeletal muscle [PDF]

, 1986
Richard Horn, Einar Lystad, A. Adler, Otto Walaas   +3 more
openalex   +1 more source

A validation study of the in vitro performance of hypoxic red blood cells for transfusion across centers in Europe

Transfusion, Volume 65, Issue 12, Page 2306-2315, December 2025.
Abstract Background Refrigerated storage of red cell concentrate (RCC) leads to metabolic, oxidative, and structural changes that impair functionality and viability. These changes can be attenuated by hypoxic storage. Objective This study assessed the quality of leucocytes‐reduced (LR), O2/CO2 reduced red blood cells (RBC) stored for 42 days after pre ...
Vanessa Agostini, Reinhard Henschler, Turid Helen Felli Lunde, Einar Klæboe Kristoffersen, Geir Hetland, Elena Danilova, Agathe Martin, Michel Prudent, Giuliano Grazzini, Lucia De Franceschi, Iwona Walicka, Joseph Wagner, Laurel Omert   +12 more
wiley   +1 more source

ANP-ing Up Diabetes: Impaired Natriuretic Peptide Action in Muscle Forms a Mechanistic Link Between Obesity and Diabetes [PDF]

, 2015
Cleasby, M E
core   +1 more source