γδ T Cells and Inborn Errors of Immunity
This review examines inborn errors of immunity (IEIs) affecting γδ T cells, focusing on conditions that lead to their altered balance with αβ T cells. It highlights key molecular players and species differences in human and mouse models, offering insights into γδ T cell development and function with potential diagnostic and therapeutic implications ...
Sagar, Stephan Ehl
wiley +1 more source
Erectile dysfunction (ED) is a common and debilitating condition that negatively impacts men's quality of life and psychological well‐being. Excessive circulating copper levels are causally linked to an increased risk of ED, as shown by Mendelian randomization and meta‐analysis. Balanced copper intake is crucial for sexual health, highlighting the need
Zilong Wang+6 more
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Inositol 1,4,5‐trisphosphate‐ and guanosine 5′‐O‐(3‐thio triphosphate)‐induced Ca2+ release in cultured airway smooth muscle [PDF]
Lorna C. Chopra+3 more
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Dexras1/AGS-1, a Steroid Hormone-Induced Guanosine Triphosphate-Binding Protein, Inhibits 3′,5′-Cyclic Adenosine Monophosphate-Stimulated Secretion in AtT-20 Corticotroph Cells1 [PDF]
Timothy E. Graham+3 more
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The Essentiality of Amino Acids in Healthiness and Disease State: Type II Diabetes as a Case Study
This review investigates the functions of amino acids in normal physiological states, their potential as a diagnostic biomarker, the probable risk of deficiency, and the therapeutic ability for managing and preventing type 2 diabetes mellitus. ABSTRACT A healthy life depends on the availability and the synthesis of amino acids as they are building ...
Samuel Idowu Fayomi+2 more
wiley +1 more source
An insulin receptor peptide (1135-1156) stimulates guanosine 5′-[γ-thio]triphosphate binding to the 67 kDa G-protein associated with the insulin receptor [PDF]
Hanjoong Jo+3 more
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Effects of insulin and guanosine 5′-[γ-thio]triphosphate on fatty acid synthesis and lipolysis within electropermeabilized fat-cells [PDF]
Guy A. Rutter, Richard M. Denton
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Mitochondrial Transplantation: A Novel Therapeutic Approach for Treating Diseases
This article describes the roles of mitochondria in health and disease and reviews the effects of mitochondrial transplantation in disease, including restoring ATP production, attenuating oxidative stress, modulating inflammatory responses, reducing apoptosis, promoting cell repair, and exhibiting antitumor properties.
Xinglu Miao+4 more
wiley +1 more source
Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules. [PDF]
Bismark Amoah-Apraku+3 more
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