Results 191 to 200 of about 177,246 (350)
Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Annals of Neurology, Volume 98, Issue 4, Page 851-863, October 2025.Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 91, Issue 10, Page 2865-2873, October 2025.Aims Shunting (hypermethylating) thiopurine metabolism, characterized by excessive 6‐MMPR production and (sub)therapeutic 6‐TGN levels, poses a significant challenge in the treatment of inflammatory bowel disease (IBD). This study evaluates the metabolic outcomes of switching to low‐dose thiopurine with allopurinol (LDTA) or thioguanine (TG) in IBD ...
Ahmed B. Bayoumy +4 more
wiley +1 more source
Thyrotropin-releasing hormone and gonadotropin-releasing hormone receptors activate phospholipase C by coupling to the guanosine triphosphate-binding proteins Gq and G11. [PDF]
, 1992 Kai Hsieh, Thomas F.J. Martin
openalex +1 more source
Cancer Communications, Volume 45, Issue 10, Page 1309-1333, October 2025.Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang +9 more
wiley +1 more source
Cancer Communications, Volume 45, Issue 10, Page 1285-1308, October 2025.Abstract Background Eps15 homology domain (EHD) proteins, including EHD1 to EHD4, play vital roles in tumor progression. In this study, we aimed to investigate which specific EHD proteins, if any, are implicated in tumor immune evasion and immunotherapy response.
Fanglin Tian +11 more
wiley +1 more source
Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules. [PDF]
, 1995 Bismark Amoah-Apraku +3 more
openalex +1 more source