Results 191 to 200 of about 83,988 (248)

Soluble guanylate cyclase induces cranial vasodilation and headache in adults: a randomized trial. [PDF]

open access: yesBrain Commun
Rasmussen NB   +7 more
europepmc   +1 more source

Controlled Delivery and Light-Induced Release of Magic Spot Nucleotides in Escherichia coli

open access: yes
Popp C   +10 more
europepmc   +1 more source

Controlling Supramolecular Fiber Formation of Nucleopeptide by Guanosine Triphosphate

Biomacromolecules, 2023
Cells use dynamic self-assembly to construct functional structures for maintaining cellular homeostasis. However, using a natural biological small molecule to mimic this phenomenon remains challenging. This work reports the dynamic microfiber formation of nucleopeptide driven by guanosine triphosphate, the small molecule that controls microtubule ...
Hongyue Zhang   +7 more
openaire   +2 more sources

Synthesis of Guanosine-Containing Dinucleoside Triphosphates

Advanced Materials Research, 2014
Dinucleoside polyphosphates have potential medicinal value and are of substantial interest to both synthetic and medicinal chemists. A practical method for the synthesis of guanosine-containing asymmetrical dinucleoside triphosphates (Gp3C and Gp3U) with 4,5-dicyanoimidazole as activator has been developed.
Yue Hai You, Shan Shan Gong, Qi Sun
openaire   +1 more source

Interactions of tubulin with vinblastine and guanosine triphosphate

Journal of Molecular Biology, 1972
Abstract Tubulin isolated from calf brain contains one mole of tightly bound nucleotide per 120,000 g of protein, chiefly as GDP. Another mole of GTP can be bound in exchange with the medium. Transphosphorylation occurs between the terminal phosphate of the exchangeable nucleotide and the tightly bound GDP.
R W, Berry, M L, Shelanski
openaire   +2 more sources

[37] Guanosine triphosphate-8-formylhydrolase

1975
Publisher Summary This chapter discusses the assay and purification procedure of guanosine triphosphate-8-formylhydrolase. The assay method is based on two procedures. The first method involves the release of 14 C-labeled formic acid from carbon-8 of the imidazole ring of [8- 14 C]GTP. The formic acid is oxidized to carbon dioxide. The second method
E.F. Elstner, R.J. Suhadolnik
openaire   +1 more source

Repetitive recycling of guanosine triphosphate cyclohydrolase I for synthesis of dihydroneopterin triphosphate

Analytical Biochemistry, 1989
A procedure for enzymatic production of dihydroneopterin triphosphate is described that allows GTP cyclohydrolase I to be reused repetitively. The reaction takes place in an ultrafiltration cell, and the product is collected in the filtrate, whereas the enzyme remains in the cell to be reused with additional substrate. This is repeated until the enzyme
J, Ferre, E W, Naylor, K B, Jacobson
openaire   +2 more sources

Direct incorporation of guanosine 5-diphosphate into microtubules without guanosine 5'-triphosphate hydrolysis

Biochemistry, 1986
Using highly purified calf brain tubulin bearing [8-14C]guanosine 5'-diphosphate (GDP) in the exchangeable nucleotide site and heat-treated microtubule-associated proteins (both components containing negligible amounts of nucleoside diphosphate kinase and nonspecific phosphatase activities), we have found that a significant proportion of exchangeable ...
E, Hamel, J K, Batra, C M, Lin
openaire   +2 more sources

Neonatal hyperphenylalaninemia presumably caused by guanosine triphosphate-cyclohydrolase deficiency

The Journal of Pediatrics, 1985
C'est la recherche systematique des pteridines dans les urines qui a permis de suspecter le deficit en GTP-cyclohydrolase, 1ere etape de la synthese de la tetrahydrobiopterine (BH 4 ) chez un bebe hyperphenylalaninemique (HPA). Le deficit en BH 4 , variante rare de l'HPA, differe de la PKU classique par le caractere evolutif de l'atteinte neurologique ...
J L, Dhondt   +6 more
openaire   +2 more sources

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