Results 41 to 50 of about 40,447 (213)
Adenosine prevents TNFα-induced decrease in endothelial mitochondrial mass via activation of eNOS-PGC-1α regulatory axis. [PDF]
PLoS ONE, 2014 We tested whether adenosine, a cytoprotective mediator and trigger of preconditioning, could protect endothelial cells from inflammation-induced deficits in mitochondrial biogenesis and function.
Theodore J Kalogeris +2 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2014 Atrial natriuretic factor receptor guanylate cyclase, ANF-RGC, was the first discovered member of the mammalian membrane guanylate cyclase family. The hallmark feature of the family is that a single protein contains both the site for recognition of the ...
Teresa eDuda +2 more
doaj +1 more source
Soluble Guanylate Cyclase [PDF]
Circulation, 2009 Arthur Kornberg, who shared with Severo Ochoa the 1959 Nobel Prize for Physiology or Medicine, stated in his autobiography that he had never met a dull enzyme.1 We strongly believe that soluble guanylate cyclase (sGC; E.C.4.6.1.2) is no exception to this.
Guido, Boerrigter, John C, Burnett
openaire +2 more sources
Frontiers in Molecular Neuroscience, 2018 Over 100 mutations in GUCY2D that encodes the photoreceptor guanylate cyclase GC-E are known to cause two major diseases: autosomal recessive Leber congenital amaurosis (arLCA) or autosomal dominant cone-rod dystrophy (adCRD) with a poorly understood ...
Hanna Wimberg +8 more
doaj +1 more source
Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]
, 2019 Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust +9 more
core +2 more sources
ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice. [PDF]
, 2017 There is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries.
Li, Peng +3 more
core +2 more sources
Identification of bacterial guanylate cyclases [PDF]
Proteins: Structure, Function, and Bioinformatics, 2017 The ability of bacteria to use cGMP as a second messenger has been controversial for decades. Recently, nucleotide cyclases from Rhodospirillum centenum, GcyA, and Xanthomonas campestris, GuaX, have been shown to possess guanylate cyclase activities. Enzymatic activities of these guanylate cyclases measured in vitro were low, which makes interpretation
Min-Hyung, Ryu +3 more
openaire +3 more sources
Role of guanylyl cyclase modulation in mouse cone phototransduction [PDF]
, 2011 A negative phototransduction feedback in rods and cones is critical for the timely termination of their light responses and for extending their function to a wide range of light intensities. The calcium feedback mechanisms that modulate phototransduction
Chen, Jeannie +2 more
core +2 more sources
Liberators of NO exert a dual effect on renin secretion from isolated mouse renal juxtaglomerular cells [PDF]
, 1993 This study aimed to examine the role of nitric oxide (NO) in the regulation of renin secretion from renal juxtaglomerular (JG) cells. Using primary cultures of mouse renal JG cells, we found that sodium nitroprusside (SNP) and 3-morpholino-sydnonimin ...
Kurtz, Armin, Schricker, K.
core +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source