Results 161 to 170 of about 166,028,058 (335)
Question 1: Origin of Life and the Living State
, 2007 Question 1: Origin of Life and the Living ...
Stuart Kauffman
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Assessing the Economic Value of Credit Guarantees [PDF]
This article analyzes how a credit guarantee confers private benefits to creditors and proposes reform policies and related assessment measures in order to make credit guarantee a socially beneficial intermediation instrument. Analysis indicates that the
Saldaña, Cesar G.
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"The Right to a Job, the Right Types of Projects: Employment Guarantee Policies from a Gender Perspective" [PDF]
There is now widespread recognition that in most countries, private-sector investment has not been able to absorb surplus labor. This is all the more the case for poor unskilled people.
Rania Antonopoulos
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Soil and Water Conservation Works through National Rural Employment Guarantee Scheme (NREGS) in Andhra Pradesh — An Analysis of Livelihood Impact [PDF]
The impact of National Rural Employment Guarantee Scheme (NREGS) has been studied on rural livelihoods and the nature of soil and water conservation (SWC) works.
Kumar, Shalander +4 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Reconstitution of Institutional Guarantee Theories within the Constitution of Japan
, 2011 This paper attempts to“revive”and reconstitute traditional theories on institutional guarantee within the Constitution of Japan, which seem to have been“suffocated”with a number of academic criticisms.
海野, 敦史
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Ars Iuris Salmanticensis, 2019 In the present work, we examine the origins of administrative guarantees, going back to France in the 18th century, and their counterpart in the Spanish legal order of the 19th century. In France, administrative guarantees are achieved in the hierarchical appeal, which becomes the appeal for abuse of power, together with the appeal for full ...
openaire +1 more source