Results 51 to 60 of about 144,701 (287)

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

Data Selective Rake Reception for Underwater Acoustic Communication in Strong Multipath Interference

open access: yesJournal of Electrical and Computer Engineering, 2017
In underwater acoustic communication (UAC), very long delay waves are caused by reflection from water surfaces and bottoms and obstacles. Their waves interfere with desired waves and induce strong multipath interference.
Shingo Yoshizawa   +2 more
doaj   +1 more source

The Prediction of Road-Accident Risk through Data Mining: A Case Study from Setubal, Portugal

open access: yesInformatics, 2023
This work proposes a tool to predict the risk of road accidents. The developed system consists of three steps: data selection and collection, preprocessing, and the use of mining algorithms.
David Dias   +2 more
doaj   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

Zero-Forcing Frequency-Domain Equalization for Generalized DMT Transceivers with Insufficient Guard Interval

open access: yesEURASIP Journal on Advances in Signal Processing, 2004
We propose a zero-forcing frequency domain block equalizer for discrete multitone (DMT) systems with a guard interval of insufficient length. In addition to the insufficient guard interval in the time domain, the equalizer takes advantage of frequency ...
Trautmann Steffen   +2 more
doaj   +1 more source

Complex belemnites of the Puaroan (lower-? middle Tithonian) stage in the Port Waikato Region of New Zealand [PDF]

open access: yes, 1970
Belemnite guards range through 2700 feet of Puaroan strata in the Port Waikato region. All are Belemnopsis of the uhligi-complex. Belemnopsis aucklandica aucklandica (Hochstetter) in its most typical form may be restricted to the lower 700 feet of the ...
Challinor, A.B.
core   +1 more source

A Novel Data-Aided Channel Estimation with Reduced Complexity for TDS-OFDM Systems [PDF]

open access: yes, 2012
In contrast to the classical cyclic prefix (CP)-OFDM, the time domain synchronous (TDS)-OFDM employs a known pseudo noise (PN) sequence as guard interval (GI).
Crussière, Matthieu   +2 more
core   +5 more sources

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

HySIA: Tool for Simulating and Monitoring Hybrid Automata Based on Interval Analysis

open access: yes, 2017
We present HySIA: a reliable runtime verification tool for nonlinear hybrid automata (HA) and signal temporal logic (STL) properties. HySIA simulates an HA with interval analysis techniques so that a trajectory is enclosed sharply within a set of ...
A David   +12 more
core   +2 more sources

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

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