Results 91 to 100 of about 802,501 (350)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Pengaruh Suku Bunga Terhadap Aktivitas Perdagangan Saham (Studi Pada Bursa Efek Indonesia Periode 2005-2014) [PDF]

open access: yes, 2015
The purpose of this study is to examine the effect of BI Rate and FED Rate partially and simultaneously on stock trading volume, stock trading value, and stock trading frequency by using multiple linear regression analysis.
Muhammad, G. (Guardian)
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Practice of Elopements in Pakistan: An Analytical Study of Runway Marriages in Contemporary Islamic Law [PDF]

open access: yesHazara Islamicus, 2018
In Islamic law, marriage is a bond conducted between the genders after certain considerations. The purpose of marriage is to join the two persons and their families for the betterment of the family and society.
Muhammad Ifzal Mehmood   +1 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

FEATURES OF REAL ESTATE TRANSACTIONS BY GUARDIANS OF A MINOR [PDF]

open access: yesLegal Bulletin
The article is devoted to the features and modern problems of implementing the rights of minors when concluding real estate transactions. Despite the fact that ensuring legal guarantees for minors when making transactions with their property is one of ...
VERKHOVA D.V.
doaj   +1 more source

Silent Guardian: The 15th New Jersey Monument

open access: yes, 2015
This post is part of a series featuring behind-the-scenes dispatches from our Pohanka interns working on the front lines of history this summer as interpreters, archivists, and preservationists. See here for the introduction to the series.
Smith, Elizabeth A.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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