Results 111 to 120 of about 802,501 (350)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Why it matters who edits the Guardian [PDF]
, 2015 Imagine a north London liberal journalist version of The Apprentice. This week, four Guardian hacks (one ex-Guardian) will perform in front of their newsroom colleagues as part of hustings to win the vote for the editorship of the Kings Place ...
Beckett, Charlie
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
İstanbul Hukuk MecmuasıThe provision of Article 407/1 of the Turkish Civil Code, which mandates that every adult who has been sentenced to a term of imprisonment of one year or longer, along with the related provisions of Articles 407/2 and 471 of the same Code, have been ...
Caner Taşatan
doaj +1 more source
An Investigation of Philadelphia's Youth Aid Panel: A Community-Based Diversion Program for First-Time Youthful Offenders [PDF]
, 2000 The formal justice system currently does not have the resources to effectively deal with nonviolent first-time offending youth, oftentimes leaving them with little punishment aside from a criminal record.
Bernardine H. Watson, Nina W. Chernoff
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Transformation of a Charity Shop into a Specialist Fashion Store [PDF]
, 2010 More than ten years ago, a Guardian columnist observed a growth in the charity shop sector due to an increase in the number of such outlets on the high streets of towns and cities in the UK.
Cassidy, Thomas +2 more
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