Results 41 to 50 of about 7,313 (236)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2013 At the second half of the XIX century in villages and farms of the Don Cossack Host there were various options of guardianship and guardianship over juvenile and minor children who were generally regulated not by standards of the official legislation ...
Krasnov Sergey Yurievich
doaj +1 more source
Reflection of Revelation in the Poetries of Kumait-Ibn-Zaid Asadi [PDF]
آموزههای قرآنی, 2019 The Holy Quran has always been the source of artistic inspiration and literary creations of Arabs. In summary, the impact of this heavenly book has two layers: intellectual, and linguistic.
Hamid Abbas Zadeh
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Art Vandalism and Guardianship in US Art Institutions
Arts, 2018 Art crime scholars and art world professionals constantly grapple with determining the most effective methods by which to reduce and prevent victimization by art vandals.
Katharine Salomon +4 more
doaj +1 more source
Namık Kemal Tıp Dergisi, 2023 Aim:We aimed to compare the sociodemographic and clinical variables of the patients with bipolar disorder (BD), who were required guardianship by Mental Health Hospital’s Health Board.Materials and Methods:This retrospective study consisted of 201 ...
Filiz KULACAOĞLU +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
THE PURPOSE OF LAW, PANCASILA AND LEGALITY ACCORDING TO ERNST UTRECHT: A CRITICAL REFLECTION
Indonesia Law Review, 2015 Ernst Utrecht is one of the best legal scholars Indonesia has ever had. His political views position him as an organic intellectual; a legal scholar involved in and expressing the social consciousness, both in the academic as well as in the political ...
Fernando Morganda Manullang
doaj +1 more source