Results 41 to 50 of about 106 (74)

Placental Growth Throughout the Last Two Thirds of Pregnancy in Sheep: Vascular Development and Angiogenic Factor Expression1

Biology of Reproduction, 2007
P. Borowicz, D. R. Arnold, M. L. Johnson, A. Grazul-Bilska, D. Redmer, L. Reynolds   +5 more
semanticscholar   +1 more source

Differential expression of alternative transcripts of soluble guanylyl cyclase, GYCY1a3 and GUCY1b3 genes, in the malignant and benign breast tumors

Nitric Oxide, 2019
Extensive alterations in splicing is one of the molecular indicator for human cancers. Soluble guanylyl cyclase (sGC), an obligatory heterodimer, is composed of α1 and β1 subunits. Each subunit is encoded by a separate gene, GUCY1a3 and GUCY1b3, correspondingly.
Milad Mohammadoo khorasani, Fatemeh Karami Tehrani, Seyed Mohammad Reza Parizadeh, Morteza Atri   +3 more
exaly   +6 more sources

Aspen Perinatal Biology Conference: Aspen, Colorado, August 25–28, 2007

Pediatric Research, 2007
L. Myatt, S. Davidge, B. Hay, L. Reynolds   +3 more
semanticscholar   +1 more source

Methylphenidate regulates HEY1, SLC2A3, ATXN1, GUCY1B3 and MAP3K8 in lymphoblastoid cells from adult ADHD patients

Pharmacopsychiatry, 2013
Sarah Kittel-Schneider, Lena Weißflog, R. Schwarz, Andreas Reif, CJ Scholz   +4 more
exaly   +6 more sources

Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3

Oncology Reports, 2004
Malignant gliomas, most of which show an elevated level of vascular endothelial cell growth factor (VEGF) expression, are well known for their hyper-vascularity. One of the possible inducers of VEGF in tumor cells is nitric oxide (NO), which is synthesized by NO synthase and stimulates soluble guanylate cyclase (GC) in tumor cells. Here, we report that
Takamasa Kayama, Yoshinori Murakami, Tomoko Maruyama, Takao Sekiya, M Saino   +4 more
semanticscholar   +5 more sources

The β subunit of soluble guanylyl cyclase GUCY1B3 exerts cardioprotective effects against ischemic injury via the PKCε/Akt pathway

Journal of Cellular Biochemistry, 2018
AbstractThe soluble form of guanylyl cyclase (sGC) is the main receptor for the signaling agent nitric oxide (NO), which regulates cardiomyocyte contractile function and attenuates cardiomyocyte hypertrophy. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), a regulator of vascular tone, and cardiac NO‐sGC‐cGMP signaling modulates ...
Xiaomin Wang, Wei Du, Meng Li, Yong Zhang, Hongyu Li, Kai Sun, Jianping Liu, Pengxia Dong, Xianda Meng, Wensi Yi, Liu Yang, Ruiping Zhao, Jiang Hu   +12 more
semanticscholar   +4 more sources

Open angle glaucoma in soluble guanylate cyclase α1-deficient mice and its association with the GUCY1A3/GUCY1B3 locus in humans

Nitric Oxide, 2012
Primary open angle glaucoma (POAG) is a leading cause of blindness, due to irreversible retinal ganglion cell (RGC) loss with optic nerve (ON) degeneration. Currently, there is no cure for POAG and available therapies offer incomplete protection, highlighting the need for novel drug targets.
Laurel T. Tainsh, Stephanie J. Loomis, Emmanuel S. Buys, Louis R. Pasquale, Louis R. Pasquale, Douglas J. Rhee, Janey L. Wiggs, Alexander Jones, Sarah R Hayton, Robert E. Tainsh, Rajeev Malhotra, Emma Abernathy, Yu-Chieh Ko, Dong-Jin Oh, Ruiyi Ren, Bruce R. Ksander, J. H. Kang, Haiyan Gong, Peter Brouckaert, Meredith S. Gregory, Kenneth D. Bloch   +20 more
semanticscholar   +5 more sources

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A preliminary study on methylphenidate-regulated gene expression in lymphoblastoid cells of ADHD patients

World Journal of Biological Psychiatry, 2015
Klaus-peter Lesch, Claus-jürgen Scholz, Heike Weber   +2 more
exaly   +2 more sources

Effects of estradiol-17β on expression of mRNA for seven angiogenic factors and their receptors in the endometrium of ovariectomized (OVX) ewes

Endocrine, 2006
Lawrence P Reynolds
exaly   +2 more sources

Co-expression of soluble guanylyl cyclase subunits and PDE5A shRNA to elevate cellular cGMP level: A potential gene therapy for myocardial cell death.

Technology and Health Care, 2022
BACKGROUND Genetic manipulation on the NO-sGC-cGMP pathway has been rarely achieved, partially due to complexity of the soluble guanylyl cyclase (sGC) enzyme.
G. Jing, Zhang Xia, Quan Lei
semanticscholar   +1 more source