Results 41 to 50 of about 2,082,427 (238)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Guide dog mobility from the client's perspective
, 2002 The successful guide dog enhances the lifestyle of the guide dog user by enabling independent mobility, providing companionship and facilitating social-interaction.
Lloyd, Janice K.F.
core +1 more source
AnimalsAssistance animal (AA) trainers could develop compassion satisfaction (CS) but also compassion fatigue (CF), due to potential exposure to suffering through working with people with disabilities.
James Verrall +2 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
, 2008 Thesis discusses about blind people, guide-dogs and their benefits. Thesis describes the troubles of blind in daily life, insufficient guide-dog's legislation and also negative experiences of blind with hospital staff.
Bártová, Lucie
core
Dog guides as witnesses with specific reference to Miles and Houellebecq
Tydskrif vir Letterkunde, 2018 Since Wild Dog first crawled from the Wet Wild Woods and laid his head on Woman’s lap, he has helped man, not only to hunt and protect, but also as guide. A guide with enhanced senses in the physical world who could find a way across unmarked landscapes,
Catherine du Toit
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A colony of dog guides: analysis of the genetic variability assessed by pedigree data
Italian Journal of Animal Science, 2010 The study presents the analysis of the genetic variability in a colony of dog guides. Three breeds, Labrador (L), Golden Retriever (GR), and German Shepherd (GS), were evaluated.
Roberta Ciampolini +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source