Results 91 to 100 of about 1,893,825 (286)
The effects of assistance dogs on psychosocial health and wellbeing: A systematic literature review.
PLoS ONE, 2020 Beyond the functional tasks that assistance dogs are trained for, there is growing literature describing their benefits on the psychosocial health and wellbeing of their handlers.
Kerri E Rodriguez +4 more
doaj +1 more source
USFSP Library Hosts Guide Dogs-in-Training
, 2017 Keep an eye out around the library for Juno (4 months) and Conway (5 months) our on-site guide dogs-in-training. Valeria, a student worker and Steph, an Instructional Designer, and are both puppy raisers for the Southeastern Guide Dogs organization.https:
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2023 The project aims to explore how visually impaired people build cooperation and communication with guide dogs. Equally important is to identify the cultural and social determinants and consequences of this relationship.
Pietrowiak, Kamil
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
TFP-YOLO: Obstacle and Traffic Sign Detection for Assisting Visually Impaired Pedestrians
SensorsWith the increasing demand for intelligent mobility assistance among the visually impaired, machine guide dogs based on computer vision have emerged as an effective alternative to traditional guide dogs, owing to their flexible deployment and scalability.
Zhiwei Zheng, Jin Cheng, Fanghua Jin
doaj +1 more source
Dog guides as witnesses with specific reference to Miles and Houellebecq
Tydskrif vir Letterkunde, 2018 Since Wild Dog first crawled from the Wet Wild Woods and laid his head on Woman’s lap, he has helped man, not only to hunt and protect, but also as guide. A guide with enhanced senses in the physical world who could find a way across unmarked landscapes,
Catherine du Toit
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source