Results 61 to 70 of about 1,893,825 (286)

Geographic Availability of Assistance Dogs: Dogs Placed in 2013–2014 by ADI- or IGDF-Accredited or Candidate Facilities in the United States and Canada, and Non-accredited U.S. Facilities

open access: yesFrontiers in Veterinary Science, 2019
Assistance dogs' roles have diversified to support people with various disabilities, especially in the U.S. Data presented here are from the U.S. and Canada non-profit facilities (including both accredited and candidate members that fulfilled partial ...
Sandra Walther   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Guide Dogs of Texas Evaluation Summary [PDF]

open access: yes, 2014
Kronkosky Charitable FoundationEvaluation Summary:  Guide Dogs of Texas, San Antonio, TXOperations grant, with $2 for $1 KCF matching, in support of providing services to the blindand visually impaired to improve mobility and ...

core   +2 more sources

Reproduction of dogs in the tropics [PDF]

open access: yes, 2006
Dog overpopulation is considered a serious problem in developing countries and a threat to human health. To be successfully implemented, official dog control measures have to be in accordance with regional beliefs and practices of an area.
Ortega-Pacheco, Antonio
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Retrograde intubation in a dog with severe temporomandibular joint ankylosis: case report

open access: yesBMC Veterinary Research, 2018
Background Orotracheal intubation in dogs is a common and easily-performed procedure that provides a patent airway during anaesthesia. In dogs with temporomandibular joint ankylosis or pseudo-ankylosis, airway management can be a challenging procedure ...
Verónica Vieitez   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Covid-19: The effects of isolation and social distancing on people with vision impairment

open access: yes, 2020
This report presents findings from research on the effects of Covid-19 on people with vision impairment, based on a survey of 937 respondents. The survey contained closed questions and open free text questions, both of which are analysed in this report ...

core   +5 more sources

Preliminary Analysis of Collar Sensors for Guide Dog Training Using Convolutional Long Short-Term Memory, Kernel Principal Component Analysis and Multi-Sensor Data Fusion

open access: yesAnimals
Guide dogs play a crucial role in enhancing independence and mobility for people with visual impairment, offering invaluable assistance in navigating daily tasks and environments.
Devon Martin   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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