Results 61 to 70 of about 4,853,764 (304)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

CNN–Transformer Fusion Network With Guided Deconvolution Block for Edge-Aware Depth Completion

open access: yesIEEE Access
Depth completion has become a fundamental technology in computer vision and autonomous driving systems, enabling more accurate and detailed 3D mapping by reconstructing fine geometric structures, improving depth accuracy, and enhancing spatial continuity
Youn-Ho Choi, Seok-Cheol Kee
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Enhanced pix2pix Dehazing Network with Guided Filter Layer

open access: yesApplied Sciences, 2020
In this paper, we propose an enhanced pix2pix dehazing network, which generates clear images without relying on a physical scattering model. This network is a generative adversarial network (GAN) which combines multiple guided filter layers.
Qirong Bu   +4 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Infrared and Visible Image Fusion through Details Preservation

open access: yesSensors, 2019
In many actual applications, fused image is essential to contain high-quality details for achieving a comprehensive representation of the real scene. However, existing image fusion methods suffer from loss of details because of the error accumulations of
Yaochen Liu   +3 more
doaj   +1 more source

A Multi-Scale Superpixel-Guided Filter Feature Extraction and Selection Approach for Classification of Very-High-Resolution Remotely Sensed Imagery

open access: yesRemote Sensing, 2020
In this article, a novel feature selection-based multi-scale superpixel-based guided filter (FS-MSGF) method for classification of very-high-resolution (VHR) remotely sensed imagery is proposed.
Sicong Liu   +6 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Edge-Aware Filter Based on Adaptive Patch Variance Weighted Average

open access: yesIEEE Access, 2021
Edge-aware smoothing is an essential tool for computer vision, graphics and photography. In this paper, we develop a new and efficient local weighted average filter for edge-aware smoothing.
Fernando J. Galetto   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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