Results 171 to 180 of about 3,716,969 (351)

Pembelajaran Biologi Dengan Guided Inquiry Model Menggunakan Lks Terbimbing Dan Lks Bebas Termodifikasi Ditinjau Dari Kreativitas Dan Motivas Berprestasi Siswa [PDF]

, 2013
-Tujuan penelitian ini adalah untuk mengetahui pengaruh pembelajaran biologi dengan Guided Inquiry Model menggunakan LKS terbimbing dan LKS bebas termodifikasi, kreativitas, motivasi berprestasi siswa, serta interaksinya terhadap prestasi belajar siswa ...
Sugiyarto, S. (Sugiyarto), Sukimarwati, J. (Juli), Sunarno, W. (Widha)   +2 more
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Building the lac Operon: A Guided-Inquiry Activity Using 3D-Printed Models. [PDF]

J Microbiol Biol Educ, 2020
Gordy CL, Sandefur CI, Lacara T, Harris FR, Ramirez MV.   +4 more
europepmc   +1 more source

Physics Learning Using Inquiry-Student Team Achievement Division (ISTAD) and Guided Inquiry Models Viewed by Students Achievement Motivation [PDF]

, 2017
This study aims to determine the differences in learning outcomes of between students that are given the Physics learning models of Inquiry-Student Team Achievement Division (ISTAD) and guided inquiry, between students who have high achievement ...
Sukarmin, S. (S), Sulistijo, S. H. (S), Sunarno, W. (W)   +2 more
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Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

EFEKTIVITAS PENGGUNAAN METODE PRAKTIKUM BERBASIS GUIDED INQUIRY TERHADAP PEMBELAJARAN SISWA SMA KELAS XI PADA MATERI SISTEM KOORDINASI [PDF]

, 2016
Penelitian ini bertujuan untuk menguji efektivitas praktikum berbasis guided inquiry berdasarkan ketercapaian tujuan pembelajaran dan kesesuaian perencanaan dan pelaksanaan pembelajaran.
Yovina, Yessa Yuanita
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CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Application of Guided Inquiry Model Character Based to Improve Ability of Student on Social Problem Learning [PDF]

, 2017
This research was backgrounded by problem in 4th grade of primary school that is lack of critical thinking ability of student on social studies learning.
Istianti, T. (Tuti), Sintia, I. (Intan)
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