Results 191 to 200 of about 32,132 (260)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Fostering childhood prosociality and relatedness: the perceived impact of an arts-based philosophical intervention on collaboration, empathy and respect. [PDF]

Front Health Serv
Gilbert M, Montanez J, Fry ZD, Mendrek A, Malboeuf-Hurtubise C.   +4 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The Palette of Science and Emotions: Art-Based Learning With Structured Peer Role-Plays for Early Clinical Exposure in Biochemistry. [PDF]

MedEdPORTAL
Surapaneni KM.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Turning toward mortality: yoga's <i>savasana</i> as a salutogenic practice for engaging with death anxiety. [PDF]

Front Public Health
Rubenstein Fazzio L, Pitman A, Prosko S.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A Large Language Model-Powered Multiagent Framework Emulating Standardized Patients in Clinical Communication Skills Training: Development and Evaluation Study. [PDF]

J Med Internet Res
Qu Y, Xu X, Long Y, Wang Y, Li J, Lu X.
europepmc   +1 more source

Sustaining the Long-Term Care Workforce: An Appreciative Inquiry into the Relational and Generative Factors Driving Staff Retention. [PDF]

Sage Open Aging
Wong JOY, Wong KLY, Zhao Y, Meng C, Lin M, Boucher NA, Hung L.   +6 more
europepmc   +1 more source

Assessing personality profile: A qualitative study from drug abuse rehabilitation policies. [PDF]

MethodsX
Purwandari E, Japar M, Asyanti S, Giri RS, Yuliatun I, Madyaningrum E, Widyarini N.   +6 more
europepmc   +1 more source