Results 81 to 90 of about 71,451 (265)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigation of Meta-structures' Influence on Guided WaveProperties in Nondestructive Testing
e-Journal of Nondestructive TestingThis study explores the application of periodic structures (metamaterials) for energy focusing and mode transformation in guided waves, focusing on high-frequency Lamb wave modes.
Jiannan Zhang, Younho Cho, Young H Kim
doaj +1 more source
Converting the guided-modes of Bloch surface waves with surface pattern. [PDF]
J Opt Soc Am B, 2021 Tang XI +6 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Advances in Civil Engineering, 2012 Guided wave technique is an efficient method for monitoring structural integrity by detecting and forecasting possible damages in distributed pipe networks.
Rais Ahmad, Tribikram Kundu
doaj +1 more source
Design and Analysis of a Graphene Magneto-Plasmon Waveguide for Plasmonic Mode Switch
IEEE Access, 2019 In this paper, we design and investigate a graphene magneto-Plasmon waveguide for plasmonic mode switch application. First, an analytical model based on effective index method is presented to extract waveguide properties, such as effective index ...
Mohsen Heidari, Vahid Ahmadi
doaj +1 more source
Quasi-Guided Modes in Titanium Dioxide Arrays Fabricated via Soft Nanoimprint Lithography. [PDF]
ACS Appl Mater Interfaces, 2021 Garcia JA +6 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source