Results 121 to 130 of about 1,518,022 (349)

Barriers to Pediatric Sickle Cell Disease Guideline Recommendations. [PDF]

, 2019
National guidelines recommend that providers counsel all patients with sickle cell anemia about hydroxyurea (HU) therapy and screen children with sickle cell anemia annually for the risk of stroke with transcranial Doppler (TCD).
Bardach, Naomi S, Cabana, Michael D, Kanter, Julie, Marsh, Anne M, Rowland, Michael, Stemmler, Peggy, Treadwell, Marsha J   +6 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Context-based task ontologies for clinical guidelines [PDF]

, 2004
Evidence-based medicine relies on the execution of clinical practice guidelines and protocols. A great deal of of effort has been invested in the development of various tools which automate the representation and execution of the recommendations ...
Ciccarese, Paolo, Kumar, Anand, Piazza, Matteo, Smith, Barry   +3 more
core  

Model and Integrate Medical Resource Available Times and Relationships in Verifiably Correct Executable Medical Best Practice Guideline Models (Extended Version)

, 2018
Improving patient care safety is an ultimate objective for medical cyber-physical systems. A recent study shows that the patients' death rate is significantly reduced by computerizing medical best practice guidelines.
Fu, Zhicheng, Guo, Chunhui, Ren, Shangping, Sha, Lui, Zhang, Zhenyu   +4 more
core   +1 more source

Primary cardioprotection with dexrazoxane in patients with childhood cancer who are expected to receive anthracyclines: recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group

, 2022
Esmée C. de Baat, Elvira C van Dalen, Renée L. Mulder, Melissa M. Hudson, Matthew J. Ehrhardt, Frederike K. Engels, Elizabeth A. M. Feijen, Heynric B. Grotenhuis, Jan M. Leerink, Livia Kapusta, Gertjan J.L. Kaspers, Remy Merkx, Luc Mertens, Roderick Skinner, Wim J. E. Tissing, Florent de Vathaire, Paul C. Nathan, Leontien C.M. Kremer, Annelies M. C. Mavinkurve‐Groothuis, Saro H. Armenian   +19 more
openalex   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Identification of Ulceration in Early Gastric Cancer before Resection is Not Easy: Need for a New Guideline for Endoscopic Submucosal Dissection Indication Based on Endoscopic Image [PDF]

, 2017
Hang Lak Lee
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analysis of spinner straightening utilizing the finite element method [PDF]

, 2019
This paper presents analysis methods utilizing the Finite Element Method for spinner straightening, and shows a guideline for optimum conditions. Two types of analysis methods were composed.
Kajikawa, Shohei, Kawasaki, Keiichiro, Kuboki, Takashi, Matsumura, Hiromichi, Ono, Tetsushi, Seimiya, Hikaru   +5 more
core  

Guidelines, guidelines, and more guidelines [PDF]

Clinical Cardiology, 2002
openaire   +2 more sources