Results 121 to 130 of about 530,203 (302)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Compliance with a Pediatric Clinical Practice Guideline for Intravenous Fluid and Electrolyte Administration

, 2009
Amanda Hurdowar, Lynn Urmson, Desmond Bohn, Denis F. Geary, Ronald M. Laxer, Polly Stevens   +5 more
openalex   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Risk of Guideline Overselling and Certainty Inflation in GPT-5 Responses: A Statement-Based Analysis of Four ESGE Colorectal Guidelines. [PDF]

Endosc Int Open
Maida M, Facciorusso A, Fuccio L, Tham T, Vitello A, Calabrese G.   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Reply: Concerns regarding the WHO guideline on infertility: implications for contemporary reproductive medicine. [PDF]

Hum Reprod
Mburu G, Ombelet W, Kucuk T, Rebar RW, Giudice LC, Boivin J, Esteves SC, Balen AH, Vuong LN, Santesso N, Brignardello-Petersen R, Kennedy R, Kiarie J, WHO Guideline Development Group.   +13 more
europepmc   +1 more source

EAN 2024 Guideline on the Diagnostic Approach to Oligo/Asymptomatic HyperCKemia

T. Kyriakides, Katina Aleksovska, C. Angelini, Zohar Argov, K. G. Claeys, M. de Visser, M. FIlosto, Ivana Jovanović, A. Kostera‐Pruszczyk, M. J. Molnar, Sabrina Sacconi, J. Schaefer, G. Siciliano, J. J. Vilchez, B. Schoser, A. Toscano   +15 more
openalex   +1 more source

Efektivitas Intervensi American Society Of Perianesthesia Nurses (ASPAN) Guideline For Normothermia Terhadap Maternal Dan Neonatus Outcome Selama Perioperatif Enhanced Recovery After Caesarean Surgery (ERACS) [PDF]

, 2022
MUSTAKIM
openalex  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The Essence of Clinical Practice Guidelines for Lumbar Spinal Stenosis, 2021: 4. Surgical Treatment

Spine Surgery and Related Research, 2023
Gen Inoue
doaj   +1 more source