Results 61 to 70 of about 670,059 (330)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Update on Treatment Guideline in Fibromyalgia Syndrome with Focus on Pharmacology

Biomedicines, 2017
Fibromyalgia syndrome (FMS) is a chronic condition with unknown aetiology. The pathophysiology of the disease is incompletely understood; despite advances in our knowledge with regards to abnormal central and peripheral pain processing, and hypothalamo ...
Sanam Kia, Ernet Choy
doaj   +1 more source

KDOQI Clinical Practice Guideline for Nutrition in CKD: 2020 Update.

American Journal of Kidney Diseases, 2020
The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) has provided evidence-based guidelines for nutrition in kidney diseases since 1999.
T. Ikizler, J. Burrowes, L. Byham-Gray, K. Campbell, J. Carrero, Winnie Chan, D. Fouque, A. Friedman, S. Ghaddar, D. J. Goldstein-Fuchs, G. Kaysen, J. Kopple, D. Teta, Angela Yee-Moon Wang, L. Cuppari   +14 more
semanticscholar   +1 more source

The international WAO/EAACI guideline for the management of hereditary angioedema – The 2021 revision and update

The World Allergy Organization Journal, 2022
Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and appropriate therapy are essential. This update and revision of the global guideline for HAE provides up-to-date consensus recommendations for the management of HAE.
M. Maurer, M. Magerl, S. Betschel, W. Aberer, I. Ansotegui, E. Aygören‐Pürsün, A. Banerji, N. Bara, I. Boccon-Gibod, K. Bork, L. Bouillet, H. Boysen, N. Brodszki, P. Busse, A. Bygum, T. Caballero, M. Cancian, A. Castaldo, D. Cohn, D. Csuka, H. Farkas, M. Gompels, R. Gower, A. Grumach, G. Guidos-Fogelbach, M. Hide, H. Kang, A. Kaplan, C. Katelaris, S. Kiani-Alikhan, Wei‐Te Lei, R. Lockey, H. Longhurst, W. Lumry, A. MacGinnitie, A. Malbrán, I. Martinez Saguer, J. M. Matta Campos, A. Nast, D. Nguyen, S. Nieto‐Martinez, R. Pawankar, J. Peter, G. Porębski, N. Prior, A. Reshef, M. Riedl, B. Ritchie, Farrukh R. Sheikh, William B. Smith, P. Spaeth, M. Stobiecki, E. Toubi, L. Varga, K. Weller, A. Zanichelli, Y. Zhi, B. Zuraw, T. Craig   +58 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

International Digestive Endoscopy Network consensus on the management of antithrombotic agents in patients undergoing gastrointestinal endoscopy [PDF]

Clinical Endoscopy
Antithrombotic agents, including antiplatelet agents and anticoagulants, are widely used in Korea because of the increasing incidence of cardiocerebrovascular disease and the aging population. The management of patients using antithrombotic agents during
Seung Joo Kang, Chung Hyun Tae, Chang Seok Bang, Cheol Min Shin, Young-Hoon Jeong, Miyoung Choi, Joo Ha Hwang, Yutaka Saito, Philip Wai Yan Chiu, Rungsun Rerknimitr, Christopher Khor, Vu Van Khien, Kee Don Choi, Ki-Nam Shim, Geun Am Song, Oh Young Lee,   +16 more
doaj   +3 more sources

Author Guidelines

Pondicherry Journal of Nursing, 2014
Guidelines for Article Submission   SiELE journal accepts articles on research and development in the field of teaching and learning of English, linguistics, educational development, policy and cultural studies in education. To be considered for publication, the article should be presented in the following system: First page: include a title page with ...
openaire   +13 more sources

A methodological protocol for the development of a national guideline on perioperative management of gastrointestinal tumors in Germany

Perioperative Medicine
Background The success of abdominal cancer surgery depends not only on the surgery itself but is influenced by the overall perioperative management. Given the multitude of perioperative measures and the ever-increasing number of studies on perioperative ...
M. A. Willis, S. Post, M. Nothacker, M. Follmann, T. Langer, T. O. Vilz   +5 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

KDIGO clinical practice guidelines for the care of kidney transplant recipients

Трансплантология (Москва), 2016
Практическое клиническое руководство по наблюдению и лечению пациентов с пересаженной почкой предназначено для оказания помощи практикующим врачам, занимающимся лечением взрослых и детей, перенесших трансплантацию почки.
B. L. Kasiske, M. G. Zeier, J. R. Chapman, J. C. Craig, H. . Ekberg, C. A. Garvey, M. D. Green, V. . Jha, M. A. Josephson, B. A. Kiberd, H. A. Kreis, R. A. McDonald, J. M. Newmann, G. T. Obrador, F. G. Vincenti, M. . Cheung, A. . Earley, G. . Raman, S. . Abariga, M. . Wagner, E. M. Balk   +20 more
doaj   +2 more sources