Results 61 to 70 of about 113,296 (310)

Difficulties implementing a mental health guideline: an exploratory investigation using psychological theory. [PDF]

, 2007
Background: Evaluations of interventions to improve implementation of guidelines have failed to produce a clear pattern of results favouring a particular method.
Johnston, MS, Whitty P, Pilling Stephen, J, Simmons, J, Whitty Paula, Eccles MP, Eccles, MP, Johnston Marie, Pilling, S, Garety P, Eccles, Martin P, Johnston, M, Michie, S, Garety, Philippa; id_orcid, Michie, Susan, Eccles Martin P, Simmons J, Garety, P, Whitty, P, Garety Philippa, Simmons Jemma, Michie S, Johnston, Marie, Simmons, Jemma, Pilling, Stephen, Pilling S, Johnston M, Whitty, Paula, Michie Susan   +29 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Non-adherence to thromboprophylaxis guidelines in Atrial fibrillation: a narrative review of the extent of and factors in guideline non-adherence

, 2020
Atrial fibrillation is the most common arrhythmia. It increases the risk of thromboembolism by up to fivefold. Guidelines provide evidence-based recommendations to effectively mitigate thromboembolic events using oral anticoagulants while minimizing the ...
Gebreyohannes, EA (15722717), Salter, S (15722720), Kenneth Lee (14742088), Chalmers, L (15722723), Luke Bereznicki (14731645)   +4 more
core  

Indian guidelines for asthma: Adherence is the key

Lung India, 2015
Asthma is a common, chronic inflammatory disease of the airways that affects people of all ages and imposes a substantial burden on patients, their families, and the community.[1] It causes respiratory symptoms that are interspersed with severe attacks, which can require urgent health care and may be fatal.
Parvaiz A Koul, Dharmesh Patel
openaire   +3 more sources

Adherence to Guidelines for Youths With Diabetes Mellitus [PDF]

Pediatrics, 2011
OBJECTIVE: To describe demographic and clinical characteristics associated with self-reported receipt of tests and measurements recommended by the American Diabetes Association (ADA) for children and youths with diabetes. METHODS: The study included
Beth, Waitzfelder, Catherine, Pihoker, Georgeanna, Klingensmith, Doug, Case, Andrea, Anderson, Ronny A, Bell, Jean M, Lawrence, Elizabeth J, Mayer-Davis, Giuseppina, Imperatore, Debra, Standiford, Beatriz L, Rodriguez, Dana, Dabelea, Michael, Seid   +12 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran [PDF]

Acta Medica Iranica, 2012
Antibiotic guidelines have proven to be a simple and effective intervention to guide the choice of appropriate empiric antibiotic regimens. The goals of this study were to evaluate adherence to guidelines and streamlining of antibiotics. Hospital records
Hossein Khalili, Sepideh Elyasi, Shima Hatamkhani, Simin Dashti-Khavidaki   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Feasibility of quality indicators to assess the prevalence of guideline adherence in a german cohort of patients with advanced or metastatic breast cancer: Results of the BRE-BY-MED study

Cancer Treatment and Research Communications
Background: In Germany, the national evidence- and consensus-based S3-Guideline guide treating physicians on effective therapies. Data on guideline adherence in patients with advanced or mBC in everyday clinical practice are lacking for Germany.
Lilly Sophia Brandstetter, Anna Grau, Max Müller-Reiter, Jessica Salmen, Jens-Peter Reese, Peter U Heuschmann, Achim Wöckel   +6 more
doaj   +1 more source

ESPACOMP Medication Adherence Reporting Guideline (EMERGE) [PDF]

, 2018
Research on assessing or managing medication adherence applies approaches from observational, interventional, and implementation science that spans many disciplines and demands coherent conceptualization, valid methods, appropriate analyses, and complete
Zullig, Leah L., Helmy, Remon, Dunbar-Jacob, Jacqueline, Hughes, Dyfrig, De Geest, Sabina, Hughes, Dyfrig A., Wilson, Ira B., De Geest, S., Vrijens, Bernard, Wilson, Ira   +9 more
core   +1 more source