Results 71 to 80 of about 276,892 (360)

Evaluating the impact of policies recommending PrEP to subpopulations of men and transgender women who have sex with men based on demographic and behavioral risk factors. [PDF]

, 2019
IntroductionDeveloping guidelines to inform the use of antiretroviral pre-exposure prophylaxis (PrEP) for HIV prevention in resource-limited settings must necessarily be informed by considering the resources and infrastructure needed for PrEP delivery ...
Brown, Marshall D, Buchbinder, Susan P, Casapia, Martin, Glidden, David V, Guanira, Juan, Janes, Holly, Mayer, Kenneth H, McMahan, Vanessa M, Schechter, Mauro   +8 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Challenges with adherence to the ‘test, treat, and track’ malaria case management guideline among prescribers in Ghana

Malaria Journal, 2022
Background Despite several efforts at addressing the barriers to adherence to the WHO-supported test, treat and track (T3) malaria case management guideline in Ghana, adherence remains a challenge.
Augusta Soninour Kolekang, Yaw Afrane, Stephen Apanga, Dejan Zurovac, Anthony Kwarteng, Samuel Afari-Asiedu, Kwaku Poku Asante, Anthony Danso-Appiah   +7 more
doaj   +1 more source

Management of hypertension at the community level in Sub-Saharan Africa (SSA): towards a rational use of available resources [PDF]

, 2011
Hypertension is emerging in many developing nations as a leading cause of cardiovascular mortality, morbidity and disability in adults. In sub-Saharan African (SSA) countries it has specificities such as occurring in young and active adults, resulting in
Twagirumukiza, Marc, Van Bortel, Lucas
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Adherence to European Society of Cardiology guidelines at discharge after Acute Coronary Syndrome: a two-center data from Georgia

The Egyptian Heart Journal
Background The aim of the study was to investigate the adherence to ESC guidelines in patients discharged after ACS in Georgia. Patients and methods A prospective observational study was performed in 2 cardiac hospitals in Tbilisi from March 2021 till ...
David Gogoberidze
doaj   +1 more source

Assessing guideline adherence and child abuse evaluation in infants with fractures: a retrospective quality control study

Swiss Medical Weekly
AIMS OF THE STUDY: To standardise the assessment of infants with fractures at University Children’s Hospital Zurich, a guideline was implemented in February 2021.
Liliane Raess, Georg Staubli, Michelle Seiler   +2 more
doaj   +1 more source

Real-world research and its importance in respiratory medicine [PDF]

, 2015
Peer reviewedPublisher ...
Brusselle, Guy, Chisholm, Alison, Freeman, Daryl, Price, David, Roche, Nicolas   +4 more
core   +6 more sources

Time-trends and treatment gaps in the antithrombotic management of patients with atrial fibrillation after percutaneous coronary intervention: Insights from the CHUM AF-STENT Registry. [PDF]

, 2020
BACKGROUND: The management of atrial fibrillation and flutter (AF) patients undergoing percutaneous coronary intervention (PCI) has undergone a rapid recent evolution. In 2016, the Canadian Cardiovascular Society (CCS) published expert recommendations to
Boivin-Proulx, L-A, Camm, JA, Deneault-Marchand, A, Fox, KAA, Gobeil, F, Mansour, S, Matteau, A, Potter, BJ   +7 more
core   +1 more source

Hypertension Guideline Adherence Among Nursing Home Patients [PDF]

Journal of General Internal Medicine, 2009
Adherence to hypertension guidelines in the outpatient setting is low.To evaluate adherence to JNC VII guidelines in nursing home patients.Data were obtained from the 2004 National Nursing Home Survey (NNHS), a nationally representative sample of US nursing homes. Patients with hypertension were identified using ICD-9 codes.
Paul E, Drawz, Cristina, Bocirnea, Katarina B, Greer, Julian, Kim, Florian, Rader, Patrick, Murray   +5 more
openaire   +2 more sources