Results 111 to 120 of about 905,961 (285)

The Guiding Principles in international human rights courts

open access: yesForced Migration Review, 2018
The Guiding Principles have potential to support and complement international human rights law on internal displacement but they have had little explicit consideration by international and regional human rights courts and commissions.
Deborah Casalin
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Guiding principles of generative AI for employability and learning in UK universities

open access: yesCogent Education
This article explores the implications of Generative AI in higher education institutions, focusing on its impact on academic integrity and educational policy.
Emmanuel K. Nartey
doaj   +1 more source

LOS EFECTOS DE LA SENTENCIA 31/2010 EN EL CATÁLOGO DE DERECHOS, DEBERES Y PRINCIPIOS DEL ESTATUTO DE AUTONOMÍA DE CATALUÑA: UNA DESACTIVACIÓN MÁS APARENTE QUE REAL [PDF]

open access: yesRevista d'Estudis Autonòmics i Federals, 2011
Constitutional Court Ruling 31/2010 does not declare the nullity of any ofthe precepts of Section 1, although it cannot be stated that its content istotally unscathed; firstly, because it has been reached by agreed interpretationand secondly, because it ...
Mercè Barceló i Serramalera
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Work in progress: the Guiding Principles in Georgia

open access: yesForced Migration Review, 2018
The Guiding Principles enjoy a long history of support in Georgia. However, their successful implementation is still a work in progress.
Carolin Funke, Tamar Bolkvadze
doaj  

Guiding Principles for the Practice of Integrative Physical Therapy. [PDF]

open access: yesPhys Ther, 2023
Justice C   +4 more
europepmc   +1 more source

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