Results 91 to 100 of about 905,961 (285)

Recording, Documentation, and Information Management for the Conservation of Heritage Places: Guiding Principles [PDF]

open access: yes, 2008
Provides guidance on integrating recording, documentation, and information management of territories, sites, groups of buildings, or monuments into the conservation process; evaluating proposals; consulting specialists; and controlling ...
Francois LeBlanc   +2 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Validation of Teaching and Learning Guiding Principles Instrument for Malaysian Higher Learning Institutions

open access: yesMalaysian Journal of Learning and Instruction, 2016
Purpose â€“ This study was aimed at establishing, through the validation of the Teaching and Learning Guiding Principles Instrument (TLGPI), the validity and reliability of the underlying factor structure of the Teaching and Learning Guiding Principles ...
Nurulhuda Abd Rahman   +4 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Take Action: 2008 and Beyond [PDF]

open access: yes, 2007
The Organizing Committee for the 2008 Beijing Olympic Games issued the "Beijing Olympic Action Plan," which laid out guiding principles and a series of promises as part of Beijing's preparations to be host city.In 2003,Human Rights in China (HRIC ...
Carol Wang   +2 more
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Time to apply the Guiding Principles in Nepal [PDF]

open access: yesForced Migration Review, 2008
While Nepal’s new Maoist-led government drags its heelsin implementing the country’s national policy on IDPs, theneeds of those displaced by conflict continue to go unmet.
Shiva K Dhungana
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Proteinlike behavior of a spin system near the transition between ferromagnet and spin glass

open access: yes, 2001
A simple spin system is studied as an analog for proteins. We investigate how the introduction of randomness and frustration into the system effects the designability and stability of ground state configurations.
A.J. Bray   +17 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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