Results 71 to 80 of about 2,354,654 (281)

Seven Guiding Principles for Building Fellowship in SoTL

Canadian Journal for the Scholarship of Teaching and Learning
Considering the expansive context of the international Scholarship of Teaching and Learning (SoTL) community, SoTL scholars may wish to reflect and identify what exists for building and nurturing fellowship, and how they may be enacted in practice to ...
Anita Acai, Mandy Frake, Melanie Hamilton, Patrick Maher, Roselynn Verwoord, Cherie Woolmer   +5 more
doaj   +1 more source

Collection, storage and application of visitor use data in protected areas: guiding principles and case studies [PDF]

, 2005
This study draws together current practice for visitor monitoring in protected areas from around Australia and New Zealand, and builds on the existing ANZECC standards.
Wardell, M.J., Moore, S.A.
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Developing Emergent Bibliteracy: Guiding Principles For Instruction

Colombian Applied Linguistics Journal, 2011
Estamos a favor de la adopción de programas donde se desarrolle simultaneamente la lectura y la escritura en dos lenguas en colegios bilingües colombianos.
Alexis López, Yolanda Sosa Ortíz
doaj  

Direitos Humanos e Empresas: uma análise histórica sobre o tratamento das Nações Unidas conferido à temática e propostas para seu aperfeiçoamento

Homa Publica, 2020
This article approaches the essential elements for a historical understanding of the subject “human rights and business”, a theme that led to the approval by the United Nations, in 2011, of the so-called "Ruggie Guiding Principles".
Mariana Evelin Silva Leal
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Beyond the shoreline: making sense of coexistence for the marine governance realm

Ecology and Society
Coexistence, a concept long explored in other disciplines, has recently gained prominence in marine governance, driven by growing pressures from ocean industrialization and blue growth.
Claire K Crowley-Aksamit, Maaike Knol-Kauffman, Fabienne Mannherz, Kåre Nolde Nielsen   +3 more
doaj   +1 more source

Communications with Residents: Guiding Principles

, 2019
Guiding Principles: 1. Definition - Communication is defined as the giving and the receiving of information. An individual needs an opportunity to communicate, a way of communicating and a reason to communicate.
National Quality Improvement Office, HSE Disability Operations. Guiding Principles Subgroup
core