Results 61 to 70 of about 905,961 (285)

Guiding principles for sustainable bamboo forest management planning Benishangul-Gumuz Regional State (BGRS) [PDF]

open access: yes, 2019
Benishangul-Gumuz Regional State (BGRS) is the region of Ethiopia with the greatest bamboo forest cover. The resource has, however, encountered heavy degradation in recent years due to fires for farming and for hunting, mass flowering, unsustainable ...
Atmadja, Stibniati   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

La refutabilidad del sistema de epiciclos y deferentes de Ptolomeo

open access: yesPrincipia: An International Journal of Epistemology, 2010
To assert that the ancient planetary theory proposed by Ptolemy was irrefutable – at least until the telescope discovery – is a bit of a cliché. The aim of this paper is to analyze in what sense it could be said that the epicycle and deferent model ...
Christián C. Carman
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Guiding Principles and armed non-State actors

open access: yesForced Migration Review, 2018
Millions of internally displaced persons live in areas controlled by armed non-State actors. Direct humanitarian engagement with these actors is required in order to help them improve their understanding of and compliance with the Guiding Principles on ...
Carla Ruta   +2 more
doaj  

T-duality of anomalous Chern-Simons couplings

open access: yes, 2011
It is known that the anomalous D$_p$-brane Chern-Simons couplings are not consistent with the standard rules of T-duality. Using compatibility of these couplings with the linear T-duality transformations, the B-field gauge transformations and with the ...
Bachas   +29 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Eight caring technology principles: development and implementation of a framework for responsible health technology innovation

open access: yesJournal of Responsible Innovation
Successfully implementing care technology to enhance people's health-related quality of life poses several challenges. Although many technological tools are available, we lack consensus on values and principles, regulatory systems, and quality labels ...
Tania Moerenhout   +4 more
doaj   +1 more source

Expanded newborn screening: Guiding principles, concerns and relevance

open access: yesMuller Journal of Medical Sciences and Research, 2014
Since its introduction in 1960s, universal newborn screening (NBS) using the heel-prick dried blood spot samples has become an integral part of public health system in developed countries expanded to pre-symptomatic detection of specific inherited ...
Seema Pavaman Sindgikar   +1 more
doaj   +1 more source

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