Another Rare Cause of Hypertrophic Olivary Degeneration Following Cavernous Malformation Hemorrhage: A Case Report [PDF]
DiagnosticsIntroduction: Hypertrophic olivary degeneration (HOD) is a rare form of trans-synaptic degeneration involving the Guillain–Mollaret triangle, characterized by enlargement of the inferior olivary nucleus—unlike the atrophy typical of most ...
Sigita Skrastiņa +5 more
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Inferior olive lesions in autoimmune glial fibrillary acidic protein astrocytopathy: a report of two cases [PDF]
BMC NeurologyBackground Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a newly identified inflammatory nervous system disorder characterized by Immunoglobulin G autoantibodies against GFAP.
Haruka Kuwashige +12 more
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Clinical characteristics of hypertrophic olivary degeneration following brainstem or cerebellar hemorrhage [PDF]
Scientific ReportsPatients who have experienced bleeding in the posterior circulation of the brain often develop Hypertrophic Olivary Degeneration (HOD). This condition can lead to new neurological problems several months after the initial hemorrhage, potentially ...
Lin Lin, Xiaofeng Ye, Jianming Zheng
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Hypertrophic olivary degeneration secondary to brain abscess: a case report and literature review [PDF]
Frontiers in Human NeuroscienceIntroductionHypertrophic olivary degeneration (HOD) is a rare transsynaptic neurodegenerative disorder arising from disruption of the Guillain-Mollaret triangle (GMT), a neural circuit critical for motor coordination.
Shihan Tian +6 more
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Ultrahigh-resolution 7-Tesla anatomic magnetic resonance imaging and diffusion tensor imaging of ex vivo formalin-fixed human brainstem-cerebellum complex [PDF]
Frontiers in Human NeuroscienceIntroductionBrain cross-sectional images, tractography, and segmentation are valuable resources for neuroanatomical education and research but are also crucial for neurosurgical planning that may improve outcomes in cerebellar and brainstem interventions.
Sahin Hanalioglu +16 more
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Neuroscience Insights, 2021 Hypertrophic olivary degeneration is a rare condition caused by a lesion in the Guillain-Mollaret triangle which leads to trans-synaptic degeneration resulting in the degenerative hypertrophy of the inferior olivary nucleus.
Fardad Behzadi +2 more
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BMC Neurology, 2020 Background Palato-pharyngo-laryngeal myoclonus, a variant of palatal myoclonus, is characterized by involuntary rhythmic movements of palatal, pharyngeal, and laryngeal muscles.
Jamie L. Fleet +3 more
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T‐type calcium channels as therapeutic targets in essential tremor and Parkinson's disease
Annals of Clinical and Translational Neurology, Volume 10, Issue 4, Page 462-483, April 2023., 2023 Abstract Neuronal action potential firing patterns are key components of healthy brain function. Importantly, restoring dysregulated neuronal firing patterns has the potential to be a promising strategy in the development of novel therapeutics for disorders of the central nervous system.
Lillian G. Matthews +6 more
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Unilateral Holmes tremor associated with compression of the brainstem by an ectatic vertebral artery
Annals of Movement Disorders, 2020 Lesions affecting the Guillain–Mollaret triangle usually lead to palatal or oculopalatal tremors and occasionally Holmes tremors (HTs). We report two cases of unilateral HT without palatal tremor, secondary to brainstem compression by an ectatic ...
Shweta Prasad +3 more
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Palatal myoclonus secondary to neurosarcoidosis
Clinical Case Reports, 2020 Palatal myoclonus can be primary or secondary. In primary palatal myoclonus, no obvious structural brain lesions can be found within the triangle of Guillain and Mollaret.
Devanshi Dharaiya, Anza B. Memon
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