Results 51 to 60 of about 32,303 (159)
Young adult deletion of microglial C1q reduced engulfment of Vglut1+ synapses and mitigated spatial cognitive deficits at 10 months of age in the amyloidopathy Arctic mouse model of AD. Neither fibrillar amyloid plaques nor soluble or insoluble Aβ levels in the hippocampus were affected by young adult microglial loss of C1q despite reduced phagocytosis
Tiffany J. Petrisko +4 more
wiley +1 more source
GUILLAIN-BARRÉ syndrome and hemolytic anemia associated with HTLV-1 infection
Male patient, 54 years old, with a history of Guillain-Barré syndrome, treated with Gabapentin. Four months before admission presents autoimmune hemolytic anemia, treated with prednisone.
Rául Vallejos Núñez +4 more
doaj +1 more source
ABSTRACT Adult patients with inherited metabolic diseases are often overlooked. Limited data on this population hinder adequate planning of their clinical and social care. In this retrospective, observational, cross‐sectional service evaluation study, we reviewed the electronic medical records of adult patients with inherited neurometabolic diseases ...
Boel Ernerdahl +2 more
wiley +1 more source
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
ABSTRACT Background and Aims In ADHERE, subcutaneous efgartigimod PH20 (1000 mg once weekly) was effective and well tolerated in participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). ADHERE+ is an open‐label extension of ADHERE assessing long‐term safety and efficacy. Methods Eligible participants from ADHERE run‐in period
Jeffrey A. Allen +8 more
wiley +1 more source
Neurophysiological Characteristics of Nitrous Oxide‐Induced Polyneuropathy: A Case Series
ABSTRACT Background Nitrous oxide (N2O) misuse is a growing health concern, with N2O‐induced neurological disorders increasingly reported across Europe. Among these, N2O‐induced polyneuropathy (PNP) can lead to permanent deficits, yet its neurophysiological characteristics remain inconsistently described.
Tanya Elisabeth Bentley +3 more
wiley +1 more source
Background Guillain-Barré syndrome is an acute inflammatory polyradiculoneuropathy. Nearly half of patients with Guillain-Barré syndrome have cranial nerve involvement.
Udaya Ralapanawa +3 more
doaj +1 more source
ABSTRACT Objective This study aimed to investigate the potential involvement of pyruvate kinase M2 (PKM2) in the pathogenesis of Guillain–Barré syndrome (GBS). Methods Mendelian randomization (MR) analysis was used to evaluate the causal association between PKM2 expression and GBS susceptibility, with mediation analysis performed to explore immune cell‐
Shuping Liu +5 more
wiley +1 more source

