Results 141 to 150 of about 804,908 (352)

Medial septum parvalbumin‐expressing inhibitory neurons are impaired in a mouse model of Dravet syndrome

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a severe neurodevelopmental disorder caused by pathogenic variants in the SCN1A gene, which encodes the voltage‐gated sodium channel Nav1.1 α subunit. Experiments in animal models of DS—including the haploinsufficient Scn1a+/− mouse—have identified impaired excitability of interneurons in the hippocampus and ...
Limei Zhu   +5 more
wiley   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

open access: yesEpilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti   +14 more
wiley   +1 more source

GLYCOGENESIS IN THE LIVER OF THE FETAL GUINEA PIG

open access: hybrid, 1954
Andrew M. Nemeth   +2 more
openalex   +1 more source

Wolf‐Dog Hybrids Are More Fearful but as Social and Playful as Dogs

open access: yesEthology, EarlyView.
In order to understand how behavior changed during dog domestication, we used wolf‐dog hybrids as a proxy for wolves and compared their behavior in several test situations with that of the dog breeds they were mixed with. Wolf‐dog hybrids were similar to the dogs in sociability, playfulness, and aggression, but showed significantly more long‐lasting ...
Angelica Tagliarini, Hans Temrin
wiley   +1 more source

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