Results 131 to 140 of about 430,792 (252)

Spatial heterogeneity in exposure to Brucella suis and pathogenic leptospires in feral pigs across New South Wales

Australian Veterinary Journal, EarlyView.
Feral pigs (Sus scrofa) are important reservoirs for zoonotic and livestock pathogens in Australia, but robust information on the spatial distribution of pathogens in pig populations remains limited. We analysed serological data from a systematic, state‐wide surveillance program to investigate spatial heterogeneity in exposure to Brucella suis and ...
AJ Bengsen, S Comte, L Parker, C Brausch, F Silva, M Suann, ME Westman, J Geoghegan, R Powell, DM Forsyth, SR McLeod   +10 more
wiley   +1 more source

Generative artificial intelligence in higher education: Emotional tensions and ethical declaration

British Journal of Educational Technology, EarlyView.
Abstract The increasing use of Generative Artificial Intelligence (GenAI) tools such as ChatGPT in higher education has raised questions about authorship, ethical responsibility, and academic transparency. While institutional guidelines exist, many remain vague and ineffective, leaving students to interpret disclosure obligations on their own.
Yao Qu, Hui En Loo, Jue Wang
wiley   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Reproduction of guinea pigs

, 2014
Ovim je radom dan saţeti pregled fiziologije rasploĊivanja zamorĉića. Uz rasploĊivanje opisano je podrijetlo zamorĉića, njihova sistematika i domestikacija. U radu je opisana vrsta zamorĉića koja se najĉešće moţe sresti kao kućni ljubimac.
Ložnjak, Dejan
core   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

British Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source

Subregion‐specific perineuronal net remodelling in the dorsal hippocampus drives vulnerability and resilience to chronic stress: The role of venlafaxine treatment

British Journal of Pharmacology, EarlyView.
Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio, Arianna Palumbo, Maria Teresa Gallo, Filippo Umberto Tancredi Veronesi, Giorgia Cortinovis, Piotr Gruca, Magdalena Lason, Ewa Litwa, Dominika Biala, Fabio Fumagalli, Mariusz Papp, Francesca Calabrese   +11 more
wiley   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Livestock guinea pigs: a scoping review from a One Health perspective. [PDF]

Front Vet Sci
Salas-Rueda M, Rodríguez-Pazmiño AS, Carvajal-Capa MJ, Zúñiga-Velarde JJ, Orlando SA, García-Bereguiain MA.   +5 more
europepmc   +1 more source

Phloroglucinol inhibits human ureteral contractions via activation of cAMP‐PKA pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Phloroglucinol is used to treat renal colic, especially when non‐steroidal anti‐inflammatory drugs are contraindicated. This study aimed to clarify its mechanism by examining effects on human ureteral contractility and underlying signalling pathways. Experimental Approach Urinary levels of neurokinin A (NKA), substance P
Hanwen Liu, Ruize Xu, Zihan Guan, Lei Liu, Guangda Lv, Weibo Chen, Jiliang Wen, Jianing Liu, Jieke Yan, Fangxin Gong, Pan Xiao, Xiulin Zhang, Lei Zhang   +12 more
wiley   +1 more source

Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder

Children &Society, EarlyView.
Abstract Research focused on fetal alcohol spectrum disorder (FASD) is often deficit‐focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi‐structured interviews, the current study explored the perspectives of seven caregivers of adolescents ...
Kelly Skorka, Jodie Copley, Catherine McBryde, Pamela J. Meredith, Natasha Reid   +4 more
wiley   +1 more source