Results 141 to 150 of about 113,058 (259)

Pharmacokinetics and Paw Withdraw Pressure in Guinea Pigs (Cavia porcellus) Treated with Transdermal Buprenorphine. [PDF]

J Am Assoc Lab Anim Sci
Kozlov S, Guerrero-Martin SM, Payne G, Kendall LV.   +3 more
europepmc   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source

hERG epitope mimic-decoy peptide corrects autoimmune-long QT syndrome in guinea pigs. [PDF]

Commun Med (Lond)
Cupelli M, Ginjupalli VKM, Reisqs JB, Sleiman Y, Becerra-Flores M, Accioli R, Lazzerini PE, Cardozo T, Boutjdir M.   +8 more
europepmc   +1 more source

Nutritionists as guinea-pigs [PDF]

British Journal of Nutrition, 1996
openaire   +2 more sources

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

Sex-Related Shape Variation and Right-Left Asymmetry in the Stylopodium and Zeugopodium of Guinea Pigs. [PDF]

Animals (Basel)
Pasicka E, Ruzhanova-Gospodinova IS, Mustafa S, Pesic A, Günay E, Manuta N, Güzel BC, Yalin EE, Gündemir O.   +8 more
europepmc   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid, Aiman Saleh A. Mohammed, Gábor Mohácsi, Benjámin Paskuj, Gergő Bitay, Jakub Tomek, Sahil Dalal, Tamás Árpádffy‐Lovas, Vivien Demeter‐Haludka, István Koncz, Muhammad Naveed, László Virág, Norbert Nagy, András Varró, István Baczkó, Norbert Jost, Zsófia Kohajda, Leila Topal   +17 more
wiley   +1 more source

Pharmacokinetics of Double-Layer Patches With Microneedles Containing Procyclidine and Rivastigmine in Guinea Pigs. [PDF]

Basic Clin Pharmacol Toxicol
Moon M, Won J, Lee YW, Jeon S, Yoon Y, Jeong JH, Kang W.   +6 more
europepmc   +1 more source

Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia

The Journal of Physiology, EarlyView.
Abstract figure legend The double‐edged sword of brain sparing. Fetal hypoxaemia triggers a coordinated adaptive response characterised by redistribution of cardiac output toward essential organs, including the brain, and a reduction in overall metabolic activity to preserve oxygen supply.
Beth J. Allison, Tegan A. White, Emily J. Camm, Suzanne L. Miller   +3 more
wiley   +1 more source