Results 141 to 150 of about 230,938 (301)

Paracetamol prescribing to small animals by veterinarians in Australia and New Zealand

open access: yesAustralian Veterinary Journal, EarlyView.
Objective To describe the prescribing patterns of paracetamol by veterinarians in Australia and New Zealand. Methods An online survey was created and distributed to veterinarians in Australia and New Zealand over a 3‐month period (July–October 2024).
A Tse, W Chee, CJ Boyd, CR Sharp
wiley   +1 more source

Generative artificial intelligence in higher education: Emotional tensions and ethical declaration

open access: yesBritish Journal of Educational Technology, EarlyView.
Abstract The increasing use of Generative Artificial Intelligence (GenAI) tools such as ChatGPT in higher education has raised questions about authorship, ethical responsibility, and academic transparency. While institutional guidelines exist, many remain vague and ineffective, leaving students to interpret disclosure obligations on their own.
Yao Qu, Hui En Loo, Jue Wang
wiley   +1 more source

Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe   +6 more
wiley   +1 more source

A comparison of virulence of intraperitoneal infection of Burkholderia mallei strains in guinea-pigs

open access: yesArchives of Razi Institute, 2015
Male guinea pigs show high susceptibility to Burkholderia mallei and have been used as animal models in glanders studies. The purpose of our study was to elucidate glanders comparative pathogenesis in guinea pigs. We present here the histological changes
Eslampanah, M.   +2 more
doaj  

The role of fluvoxamine in the treatment of endotoxin‐induced acute heart injury

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cardiovascular diseases are among the most common health problems worldwide. Inflammation plays a critical role in the pathogenesis of various heart diseases. Lipopolysaccharides (LPS) trigger inflammatory mechanisms, leading to an inflammatory response.
Ilter Ilhan   +5 more
wiley   +1 more source

Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder

open access: yesChildren &Society, EarlyView.
Abstract Research focused on fetal alcohol spectrum disorder (FASD) is often deficit‐focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi‐structured interviews, the current study explored the perspectives of seven caregivers of adolescents ...
Kelly Skorka   +4 more
wiley   +1 more source

Mechanistic Insights Into Recurrent Implantation Failure: The Lactate–H3K18la–SLC7A11 Axis Explored via Endometrial Organoid and Blastoid–Endometrial Cell Implantation Models

open access: yesCell Proliferation, EarlyView.
Clinical samples first revealed impaired lactate synthesis in RIF patients. Subsequently, using endometrial organoids and a blastoid‐endometrial cell implantation model, we demonstrated that lactate enhances endometrial receptivity via H3K18la‐mediated SLC7A11 activation.
Lingling Dong   +9 more
wiley   +1 more source

Development and validation of a Guinea pig model for concurrent allergic rhinitis and asthma using recombinant Der f 2

open access: yesBMC Pulmonary Medicine
Background This study aimed to develop a guinea pig model of concurrent allergic rhinitis and asthma. Methods Thirty-three guinea pigs were randomly divided into the control group and the experimental group.
Feng Xu   +3 more
doaj   +1 more source

Behavioural and fitness effects of experimental immune activation during incubation in a wild passerine

open access: yesIbis, EarlyView.
Incubation is vital for avian embryo development but demands significant parental investment, potentially at the cost of self‐maintenance and immune function. For example, the acute phase response (APR), a systemic reaction against inflammation, infection or tissue injury, can trigger sickness behaviours such as reduced activity and foraging.
Isabel Barreda   +4 more
wiley   +1 more source

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