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Immobilization Stress Induces BDNF in Rat Submandibular Glands
Journal of Dental Research, 2006Brain-derived neurotrophic factor (BDNF) promotes survival and differentiation of the cells of the central and peripheral nervous systems. BDNF has been identified in non-neural tissue, including the heart, lung, platelets, lymphocytes, and lacrimal glands. Immobilization stress modifies BDNF mRNA expression in some organs.
K, Tsukinoki +7 more
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Stress of Immobilization: Description and Validation of a Restraining Technique for Rats
Psychological Reports, 1981Various techniques have been developed over the past several years to study the effects of the stress of immobilization on the rat. The technique proposed in this paper provides effective restraint. It has the added advantage that potentially contaminating effects of uncontrolled secondary stressors are limited.
R, Darlington, J, Bergeron, F, Leporé
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Immobilization stress-induced anorexia is mediated independent of MyD88
NeuroReport, 2016MyD88 is an adaptor protein for the toll-like receptor, which is involved in regulating innate immune function. Lipopolysaccharide-induced activation of toll-like receptor 4 signaling induces hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation and anorexia through MyD88.
Toru, Hosoi +3 more
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Effects of immobilization stress on the pathogenesis of acute murine toxoplasmosis
Brain, Behavior, and Immunity, 1990Stress modulates a variety of immune responses. We investigated the effects of immobilization stress on the pathogenesis of acute murine toxoplasmosis, an infection in which cell-mediated immunity is of major importance in host defense. Repetitive overnight immobilization beginning 3 days prior to infection enhanced (p less than 0.05) the mortality of ...
C C, Chao +4 more
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[Anti-stress effect of dalargin in immobilization stress in rats].
Biulleten' eksperimental'noi biologii i meditsiny, 1991The function of the isolated perfused rat hearts was studied in four groups of experiments. Group 1--included the hearts of intact animals ("absolute control"), group 2--the hearts of rats subjected to 24 hour immobilization in supine position against the background of triple intramuscular injections of placebo (control), group 3 included the hearts of
G F, Dvortsin, V N, Shatalov
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Involvement of dynorphin in immobilization stress-induced antinociception in the mouse
European Neuropsychopharmacology, 2000The effect of antiserum against [Met(5)]-enkephalin, [Leu(5)]-enkephalin, beta-endorphin, or dynorphin A-(1-13) administered intracerebroventricularly (i.c.v.) or intrathecally (i. t.) on immobilization-induced antinociception was studied in ICR mice. Antinociception was assessed by the tail-flick assay. Immobilization of the mouse increased inhibition
H W, Suh, D K, Song, S O, Huh, Y H, Kim
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Anti-stress effect of astragaloside IV in immobilized mice
Journal of Ethnopharmacology, 2014Astragaloside IV, a major component extracted from the roots of Astragalus membranaceus (AM), possesses anti-inflammatory, anti-oxidative, anti-fibrotic, anti-infarction and immunoregulatory effects. To clarify anti-stress effect of AM, anxiolytic and anti-inflammatory effects of 80% ethanol extract of AM and astragaloside IV were investigated in ...
Hyun-A, Oh +3 more
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[Hemodynamic correlates of immobilization stress in the rat].
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1986Changes of the systemic and regional hemodynamics were studied in alert Wistar rats during their immobilization. Cardiac output and regional blood flows were measured with microsphere technique. The stress evoked 12% blood pressure increase, 30% cardiac output increase and 10% total peripheral vascular resistance decrease.
O S, Medvedev +2 more
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Ultrastructure of Rabbit Myocardium in the Late Period of Immobilization Stress
Bulletin of Experimental Biology and Medicine, 2001Ultrastructure of working myocardium was studied in rabbits subjected to 70-day immobilization in narrow cages excluding active movements. The structure of working cardiomyocytes, nervous apparatus, and microvascular bed in auricles were studied. Particular attention was focused on intercalated disks in muscle fibers, where separation of fasciae ...
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