Results 41 to 50 of about 112,362 (304)

Experimental pharmacological research regarding the antidepressant effect of associating doxepin and selegiline in normal mice [PDF]

open access: yes, 2019
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a ...
Chiriță, Cornel   +8 more
core   +2 more sources

The Anti-Stress Effect of Mentha arvensis in Immobilized Rats [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Stress can lead to inflammation, accelerated aging, and some chronic diseases condition. Mentha arvensis (MA) is a traditional medicine having antioxidant and anti-inflammatory activities. The present study investigated the anti-stress role of MA and fermented MA (FMA) extract in immobilized rats.
Weishun Tian   +9 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Comparison of Effects of Three Distinct Stress Models on Anxiety and/or Depression-Related Behaviors in Female Rats

open access: yesSakarya Tıp Dergisi, 2019
Objective: The aim of the present study was to compare the effects of three distinct stress protocols on anxiety/depression-related behaviors in adult female rats.Material and Methods: Adult Wistar rats were randomly divided into four groups (n=8) as ...
Zafer Şahin   +7 more
doaj  

The Effect of Hydroalcoholic Extract of Perovskia Abrotanoides on Neuronal Density of Rats under Chronic Immobility Stress

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: The number of neurons in the hippocampus can have a direct effect on its function. The plant Brazembel from the mint family may have antioxidant properties.
Maryam Tehranipour   +2 more
doaj  

Antimicrobial nano-silver non-woven polyethylene terephthalate fabric via an atmospheric pressure plasma deposition process [PDF]

open access: yes, 2015
An antimicrobial nano-silver non-woven polyethylene terephthalate (PET) fabric has been prepared in a three step process. The fabrics were first pretreated by depositing a layer of organosilicon thin film using an atmospheric pressure plasma system, then
Aziz, Gaelle   +7 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

The effect of immobilization stress and cold stress on growth of WEHI–164 fibrosarcoma cells in Balb/c mice [PDF]

open access: yes, 2010
Background: Stress gradually suppresses the immune system making the body susceptible to various diseases. The aim of this study was to show the effects of cold and immobilization stress on growth of malignant cells in Balb/c mice.
Borjian Broujeni, Seifollah.   +5 more
core  

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