Results 31 to 40 of about 69,703 (261)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A model for anomalous moisture diffusion through a polymer-clay nanocomposite

, 2002
Experimental data are reported on moisture diffusion and the elastoplastic response of an intercalated nanocomposite with vinyl ester resin matrix and montmorillonite clay filler at room temperature.
Beall, Bharadwaj, Bharadwaj, Bird, Burnside, Cai, Carter, Chen, Cohen, Colombini, Cussler, Doraiswamy, Drozdov, Fredrickson, Fukuda, Gloaguen, Gorpasi, Grim, Gurtin, Hrobarikova, Hwu, Khan, Kim, Lan, Lepoittevin, Litt, Messersmith, Messersmith, Nielsen, Patel, Petricova, Roy, Sammon, Shah, Stapf, Tong, Tortora, Uschitsky, Vanlandingham, Volzone, Witten, Wu, Xu, Xu, Yano, Yano   +45 more
core   +1 more source

Effect of peppermint oil on serum lipid peroxidation and hepatic enzymes after immobility stress in mice [PDF]

, 2012
This study was undertaken to determine the influences of various doses of peppermint oil on the hepatic enzymes, alanine transaminase, apartate tranaminase, alkaline phosphotase and gamma glutamyl transferase and the level of malondialdehyde in the serum
Mansourian, A.R., Marjani, A., Rahmati, R., Veghary, G.   +3 more
core   +2 more sources

Galectin-3 Decreases in Mice Exposed to Immobilization Stress

Stress, 2000
Using M3/38 monoclonal antibody we have analyzed effects of immobilization stress on the expression of galectin-3 in liver, spleen and peritoneal macrophages from adult RFM and C3H mice, as well as from aged C3H mice (total of 22 animals). In all analyzed tissues, immobilization stress caused a significant decrease in the expression of galectin-3 ...
Dumić, Jerka, Barišić, Karmela, Flögel, Mirna, Lauc, Gordan   +3 more
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Comparison of Effects of Three Distinct Stress Models on Anxiety and/or Depression-Related Behaviors in Female Rats

Sakarya Tıp Dergisi, 2019
Objective: The aim of the present study was to compare the effects of three distinct stress protocols on anxiety/depression-related behaviors in adult female rats.Material and Methods: Adult Wistar rats were randomly divided into four groups (n=8) as ...
Zafer Şahin, Raviye Özen Koca, Hatice Solak, Alpaslan Özkürkçüler, Pınar Çakan, Zülfikare İşık Solak Görmüş, Selim Kutlu, Aynur Koç   +7 more
doaj  

The Effect of Hydroalcoholic Extract of Perovskia Abrotanoides on Neuronal Density of Rats under Chronic Immobility Stress

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: The number of neurons in the hippocampus can have a direct effect on its function. The plant Brazembel from the mint family may have antioxidant properties.
Maryam Tehranipour, Rahele Pakjame, Saiede Zafar Balanezhad   +2 more
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Vasopressin modulates hypothalamo-pituitary activity by paracrine action during acute and chronic immobilization stress in rats [PDF]

Archives of Biological Sciences, 2011
The aim of the study was to examine changes in corticotropin releasing hormone (CRH), vasopressin (VP), adrenocorticotropin (ACTH) as well as VP3 receptor protein concentration in the hypothalamus and the pituitary of rats exposed to acute (3 h) and ...
Lakić Iva, Vujović P., Jasnić N., Đurašević S., Cvijić Gordana   +4 more
doaj   +1 more source