Results 1 to 10 of about 77,745 (214)

Modulation of the Oxidative Stress and Lipid Peroxidation by Endocannabinoids and Their Lipid Analogues [PDF]

Antioxidants, 2018
Growing evidence supports the pivotal role played by oxidative stress in tissue injury development, thus resulting in several pathologies including cardiovascular, renal, neuropsychiatric, and neurodegenerative disorders, all characterized by an altered oxidative status.
Cristina Anna Gallelli, Silvio Calcagnini, Adele Romano, Justyna Barbara Koczwara, Marialuisa De Ceglia, Donatella Dante, Rosanna Villani, Anna Maria Giudetti, Tommaso Cassano, Silvana Gaetani   +9 more
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Oxidant Stress and Lipid Peroxidation in Acetaminophen Hepatotoxicity [PDF]

Reactive Oxygen Species, 2018
Acetaminophen (APAP) overdose is the most frequent cause of liver injury and acute liver failure in many western countries. The mechanism of APAP-induced hepatocyte necrosis has been investigated extensively. The formation of a reactive metabolite and its binding to cellular proteins was initially thought to be responsible for cell death.
Hartmut, Jaeschke, Anup, Ramachandran
openaire   +2 more sources

Nitric oxide and its role in lipid peroxidation [PDF]

Diabetes/Metabolism Research and Reviews, 1999
Nitric oxide (NO) is a free radical with an unpaired electron in the highest orbital. This is why it behaves as a potential antioxidant agent by virtue of its ability to reduce other molecules. In vitro experiments support this concept inasmuch as NO is able to inhibit lipid peroxidation. However, NO is rapidly inactivated by the superoxide anion (O(*2)
VIOLI, Francesco, MARINO, Rossella, M. T. Milite, LOFFREDO, Lorenzo   +3 more
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OXIDATIVE STRESS AND LIPID PEROXIDATION IN THE NEWBORN [PDF]

Pediatric Research, 1994
Increasing appreciation of the causative role of oxidative injury in the development of many severe diseases of the newborn places great importance on the reliable assessment of lipid peroxidation. Lipid peroxidation in the erythrocyte membrane has been widely investigated but little has been reported on lipid peroxidation in the plasma The aim of the ...
Giuseppe Buonocore, Stefano Zani, Maria Angela Farnetant, Franco Bagnoli, Rodolfo Bracci   +4 more
openaire   +1 more source

Role of Oxidative Stress and Lipid Peroxidation in the Pathophysiology of NAFLD

Antioxidants, 2022
Non-alcoholic fatty liver disease (NAFLD) is characterised by an excess of hepatic fat that can progress to steatohepatitis, fibrosis, cirrhosis and hepatocarcinoma. The imbalance between lipid uptake/lipogenesis and lipid oxidation/secretion in the liver is a major feature of NAFLD.
Marta Martín-Fernández, Víctor Arroyo, Carmen Carnicero, Rebeca Sigüenza, Reyes Busta, Natalia Mora, Beatriz Antolín, Eduardo Tamayo, Patricia Aspichueta, Irene Carnicero-Frutos, Hugo Gonzalo-Benito, Rocío Aller   +11 more
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Storage stability of whole and nibbed, conventional and high oleic peanuts (Arachis hypogeae L.) [PDF]

, 2013
Peanuts are increasingly being used as nibbed ingredients in cereal bars, confectionery and breakfast cereals. However, studies on their oxidative stability in this format are limited.
Ashton, Ian P., Fielding, Louise M., Tatham, Arthur S., Wilkin, Jonathan D.   +3 more
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Nitric oxide and lipid peroxidation

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1999
Nitric oxide can both promote and inhibit lipid peroxidation. By itself, nitric oxide acts as a potent inhibitor of the lipid peroxidation chain reaction by scavenging propagatory lipid peroxyl radicals. In addition, nitric oxide can also inhibit many potential initiators of lipid peroxidation, such as peroxidase enzymes.
Hogg, Neil, Kalyanaraman, B
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Studies on ferrous ion-induced lipid peroxidation of rat liver mitochondria. I. Effect of inorganic phosphate [PDF]

, 1974
Effect of inorganic phosphate on ferrous ion- and ascorbate-induced lipid. peroxidations of isolated rat liver mitochondria was investigated. As a result it has been shown that phosphate accelerates the ferrous ion.induced lipid peroxidation; namely ...
Hashimoto, Gonosuke, Tanabe, Masatada, Wakabayashi, Hiroshi, Yamamoto, Goki, Yamamoto, Michio   +4 more
core   +1 more source

Engineering tyrosine-based electron flow pathways in proteins: The case of aplysia myoglobin [PDF]

, 2012
Tyrosine residues can act as redox cofactors that provide an electron transfer ("hole-hopping") route that enhances the rate of ferryl heme iron reduction by externally added reductants, for example, ascorbate.
Alayash A. I., Alayash A. I., Aubert C., Bolognesi M., Brandon J. Reeder, Chris E. Cooper, Dimitri A. Svistunenko, Egmond M. R., Ekberg M., Ekberg M., Gray H. B., Holt S., Lardinois O. M., McLeod L. L., Michael T. Wilson, Moore K. P., Natanson C., Nilges M. J., Peisach J., Reece S. Y., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Reeder B. J., Rogers M. S., Rova U., Rova U., Seyedsayamdost M. R., Shih C., Silaghi-Dumitrescu R., Stubbe J., Svistunenko D. A., Svistunenko D. A., Svistunenko D. A., Thompson M. K., Wilbur D. J., Yee C. S.   +39 more
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Lipid peroxidation and nitric oxide inactivation in postmenopausal women [PDF]

Arquivos Brasileiros de Cardiologia, 2003
To assess the effect of endogenous estrogens on the bioavailability of nitric oxide (.NO) and in the formation of lipid peroxidation products in pre- and postmenopausal women.NOx and S-nitrosothiols were determined by gaseous phase chemiluminescence, nitrotyrosine was determined by ELISA, COx (cholesterol oxides) by gas chromatography, and cholesteryl ...
Pereira, Isabela Rosier Olimpio, Bertolami, Marcelo Chiara, Faludi, André Arpad, Campos, Maria Fernanda, Ferderbar, Simone, Lima, Emersom Silva, Aldrighi, José Mendes, Abdalla, Dulcineia Saes Parra   +7 more
openaire   +5 more sources