Results 11 to 20 of about 74,776 (265)
Modulation of the Oxidative Stress and Lipid Peroxidation by Endocannabinoids and Their Lipid Analogues [PDF]
Antioxidants, 2018 Growing evidence supports the pivotal role played by oxidative stress in tissue injury development, thus resulting in several pathologies including cardiovascular, renal, neuropsychiatric, and neurodegenerative disorders, all characterized by an altered oxidative status.
Cristina Anna Gallelli +9 more
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Oxidant Stress and Lipid Peroxidation in Acetaminophen Hepatotoxicity [PDF]
Reactive Oxygen Species, 2018 Acetaminophen (APAP) overdose is the most frequent cause of liver injury and acute liver failure in many western countries. The mechanism of APAP-induced hepatocyte necrosis has been investigated extensively. The formation of a reactive metabolite and its binding to cellular proteins was initially thought to be responsible for cell death.
Hartmut, Jaeschke, Anup, Ramachandran
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Nitric oxide and its role in lipid peroxidation [PDF]
Diabetes/Metabolism Research and Reviews, 1999 Nitric oxide (NO) is a free radical with an unpaired electron in the highest orbital. This is why it behaves as a potential antioxidant agent by virtue of its ability to reduce other molecules. In vitro experiments support this concept inasmuch as NO is able to inhibit lipid peroxidation. However, NO is rapidly inactivated by the superoxide anion (O(*2)
VIOLI, Francesco +3 more
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OXIDATIVE STRESS AND LIPID PEROXIDATION IN THE NEWBORN [PDF]
Pediatric Research, 1994 Increasing appreciation of the causative role of oxidative injury in the development of many severe diseases of the newborn places great importance on the reliable assessment of lipid peroxidation. Lipid peroxidation in the erythrocyte membrane has been widely investigated but little has been reported on lipid peroxidation in the plasma The aim of the ...
Giuseppe Buonocore +4 more
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Role of Oxidative Stress and Lipid Peroxidation in the Pathophysiology of NAFLD
Antioxidants, 2022 Non-alcoholic fatty liver disease (NAFLD) is characterised by an excess of hepatic fat that can progress to steatohepatitis, fibrosis, cirrhosis and hepatocarcinoma. The imbalance between lipid uptake/lipogenesis and lipid oxidation/secretion in the liver is a major feature of NAFLD.
Marta Martín-Fernández +11 more
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Nitric oxide and lipid peroxidation
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1999 Nitric oxide can both promote and inhibit lipid peroxidation. By itself, nitric oxide acts as a potent inhibitor of the lipid peroxidation chain reaction by scavenging propagatory lipid peroxyl radicals. In addition, nitric oxide can also inhibit many potential initiators of lipid peroxidation, such as peroxidase enzymes.
Hogg, Neil, Kalyanaraman, B
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Lipid peroxidation and nitric oxide inactivation in postmenopausal women [PDF]
Arquivos Brasileiros de Cardiologia, 2003 To assess the effect of endogenous estrogens on the bioavailability of nitric oxide (.NO) and in the formation of lipid peroxidation products in pre- and postmenopausal women.NOx and S-nitrosothiols were determined by gaseous phase chemiluminescence, nitrotyrosine was determined by ELISA, COx (cholesterol oxides) by gas chromatography, and cholesteryl ...
Pereira, Isabela Rosier Olimpio +7 more
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Oxidation product of (+)-catechin from lipid peroxidation.
Agricultural and Biological Chemistry, 1990 To make clear which parts of the molecules contribute to the activity and how safe the oxidation products are, it is necessary to investigate the oxidation products of antioxidants from lipid peroxidation.
HIROSE, Yuko +2 more
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Is Nitric Oxide (NO) an Antioxidant or a Prooxidant for Lipid Peroxidation?
Chemical and Pharmaceutical Bulletin, 2003 Antioxidant and prooxidant effects of nitric oxide (NO) on lipid peroxidation in aqueous and non-aqueous media were examined. In an aqueous solution, NO did not induce peroxidation of unoxidized methyl linoleate (ML) and suppressed the radical initiator-induced oxidation of ML.
Hiramoto, Kazuyuki +3 more
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Oxidative stress and lipid peroxidation are upstream of amyloid pathology [PDF]
Neurobiology of Disease, 2015 Oxidative stress is a common feature of the aging process and of many neurodegenerative disorders, including Alzheimer's disease. Understanding the direct causative relationship between oxidative stress and amyloid pathology, and determining the underlying molecular mechanisms is crucial for the development of more effective therapeutics for the ...
Muriel Arimon +5 more
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