Results 1 to 10 of about 1,515,713 (252)

The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

open access: yesCell Reports, 2021
Summary: T regulatory (Treg) cells are crucial to maintain immune tolerance and repress antitumor immunity, but the mechanisms governing their cellular redox homeostasis remain elusive.
Chengxian Xu   +6 more
doaj   +2 more sources

THE EFFECT OF BROCCOLI SPROUTS ON OXIDATIVE STRESS MARKERS IN MICE FED WITH CAFETERIA DIET [PDF]

open access: yesBiotechnologia Acta, 2023
The aim of our study was to determine the ability of broccoli sprouts to influence the intensity of lipid peroxidation in mice fed a high-calorie cafeteria diet. Materials and methods. In this study, C57BL/6J mice were used. For determinatiom of lipid
V.P. DERKACHOV   +2 more
doaj   +1 more source

The Effects of Oncological Treatment on Redox Balance in Patients with Uveal Melanoma

open access: yesDiagnostics, 2023
(1) Background: Uveal malignant melanoma is the most common adult eye cancer and presents metabolic reprogramming that affects the tumoral microenvironment by altering the redox balance and producing oncometabolites.
Mihai Adrian Păsărică   +5 more
doaj   +1 more source

Photolysis of incorporated benzophenone derivatives inside compressed lipid monolayers [PDF]

open access: yesJournal of the Serbian Chemical Society, 2001
The goal of this work was to study the possibility of the occurrence of radical- type lipid peroxidation of the lipid constituents on biomembranes, in compressed monolayers, having lipoidal benzophenone photosensitizers incorporated.
Marković Dejan Z.
doaj   +3 more sources

Regulation of Ferroptosis by Lipid Metabolism

open access: yesTrends in Cell Biology, 2023
Ferroptosis is an iron-dependent lethal mechanism that can be activated in disease and is a proposed target for cancer therapy. Ferroptosis is defined by the overwhelming accumulation of membrane lipid peroxides.
Lauren E Pope, Scott J. Dixon
semanticscholar   +1 more source

Lipid Peroxidation in Neurodegeneration [PDF]

open access: yesAntioxidants, 2021
Neurodegenerative diseases have multiple social and economic impacts on society, and they are the cause of millions of deaths every year [...]
openaire   +3 more sources

Assessment of Lipid Peroxides in Multiple Biofluids of Leukoplakia and Oral Squamous Cell Carcinoma Patients-A Clinico- Biochemical Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Oral pre cancer and oral cancer results in lipid peroxidation, and assessment of lipid peroxides in body fluids may give insights into the role of anti oxidants in its management. Aim: The study was conducted to discern the varying levels
Anuradha Ganesan, Gautham Kumar N
doaj   +1 more source

Lipid peroxidation increases membrane tension, Piezo1 gating and cation permeability to execute ferroptosis

open access: yesbioRxiv, 2022
The ongoing metabolic and microbicidal pathways that support and protect cellular life generate potentially damaging reactive oxygen species (ROS).
Yusuke Hirata   +6 more
semanticscholar   +1 more source

Inhibition of ferroptosis promotes retina ganglion cell survival in experimental optic neuropathies

open access: yesRedox Biology, 2022
Retinal ganglion cell (RGC) death is a hallmark of traumatic optic neuropathy, glaucoma, and other optic neuropathies that result in irreversible vision loss.
Miao Guo   +8 more
doaj   +1 more source

A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent.

open access: yesJournal of Lipid Research, 1989
A method is described for measuring lipid peroxides by means of the color reagent of a commercially available test kit for cholesterol estimation. In principle, this assay makes use of the oxidative capacity of lipid peroxides to convert iodide to iodine,
M el-Saadani   +5 more
doaj   +1 more source

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