Lipoxygenase-mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3. [PDF]
Cancer Sci, 2017 In cancer cells the small compounds erastin and RSL3 promote a novel type of cell death called ferroptosis, which requires iron‐dependent accumulation of lipid reactive oxygen species.
Shintoku R +7 more
europepmc +5 more sources
Cell Reports, 2021 Summary: T regulatory (Treg) cells are crucial to maintain immune tolerance and repress antitumor immunity, but the mechanisms governing their cellular redox homeostasis remain elusive.
Chengxian Xu +6 more
doaj +2 more sources
Circulating Lipid Peroxides Associate with More Aggressive Tumor Phenotypes and Increased Risks of Recurrence and Mortality in Breast Cancer Patients [PDF]
Medical SciencesBackground/Objectives: Breast cancer is the most common neoplasm among women and remains the leading cause of cancer-related mortality in the female population worldwide.
Julia Fernandes Gois Orrutéa +11 more
doaj +2 more sources
Molecular mechanisms underlying the ferroptosis-induced epileptiform activity in mouse cortical slices [PDF]
Frontiers in Cellular NeuroscienceIntroductionFerroptosis, a newly defined iron-dependent programmed cell death, characterized by excessive accumulation of lipid peroxides and reactive oxygen species, is involved in epilepsy, particularly in those forms resistant to drugs.
Sara Petrillo +12 more
doaj +2 more sources
THE EFFECT OF BROCCOLI SPROUTS ON OXIDATIVE STRESS MARKERS IN MICE FED WITH CAFETERIA DIET [PDF]
Biotechnologia Acta, 2023 The aim of our study was to determine the ability of broccoli sprouts to influence the intensity of lipid peroxidation in mice fed a high-calorie cafeteria diet. Materials and methods. In this study, C57BL/6J mice were used. For determinatiom of lipid
V.P. DERKACHOV +2 more
doaj +1 more source
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
Journal of Clinical Investigation, 2000 I. Leclercq +5 more
semanticscholar +3 more sources
The Effects of Oncological Treatment on Redox Balance in Patients with Uveal Melanoma
Diagnostics, 2023 (1) Background: Uveal malignant melanoma is the most common adult eye cancer and presents metabolic reprogramming that affects the tumoral microenvironment by altering the redox balance and producing oncometabolites.
Mihai Adrian Păsărică +5 more
doaj +1 more source
Photolysis of incorporated benzophenone derivatives inside compressed lipid monolayers [PDF]
Journal of the Serbian Chemical Society, 2001 The goal of this work was to study the possibility of the occurrence of radical- type lipid peroxidation of the lipid constituents on biomembranes, in compressed monolayers, having lipoidal benzophenone photosensitizers incorporated.
Marković Dejan Z.
doaj +3 more sources
Regulation of ferroptosis by lipid metabolism.
Trends in Cell Biology, 2023 Ferroptosis is an iron-dependent lethal mechanism that can be activated in disease and is a proposed target for cancer therapy. Ferroptosis is defined by the overwhelming accumulation of membrane lipid peroxides.
Lauren E Pope, Scott J. Dixon
semanticscholar +1 more source
Lipid Peroxides and α-Tocopherol in Rat Streptozotocin-Induced Diabetes Mellitus [PDF]
, 1982 Measurement of lipid peroxides and alpha-tocopherol was undertaken in rats with streptozotocin-induced diabetes. In sera and livers in diabetic rats, the lipid peroxides increased but alpha-tocopherol decreased.
Anna Davies (377353) +5 more
core +5 more sources