Results 21 to 30 of about 1,551,463 (342)

Assessment of Lipid Peroxides in Multiple Biofluids of Leukoplakia and Oral Squamous Cell Carcinoma Patients-A Clinico- Biochemical Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Oral pre cancer and oral cancer results in lipid peroxidation, and assessment of lipid peroxides in body fluids may give insights into the role of anti oxidants in its management. Aim: The study was conducted to discern the varying levels
Anuradha Ganesan, Gautham Kumar N
doaj   +1 more source

Lipid peroxidation increases membrane tension, Piezo1 gating and cation permeability to execute ferroptosis

open access: yesbioRxiv, 2022
The ongoing metabolic and microbicidal pathways that support and protect cellular life generate potentially damaging reactive oxygen species (ROS).
Yusuke Hirata   +6 more
semanticscholar   +1 more source

Inhibition of ferroptosis promotes retina ganglion cell survival in experimental optic neuropathies

open access: yesRedox Biology, 2022
Retinal ganglion cell (RGC) death is a hallmark of traumatic optic neuropathy, glaucoma, and other optic neuropathies that result in irreversible vision loss.
Miao Guo   +8 more
doaj   +1 more source

A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent.

open access: yesJournal of Lipid Research, 1989
A method is described for measuring lipid peroxides by means of the color reagent of a commercially available test kit for cholesterol estimation. In principle, this assay makes use of the oxidative capacity of lipid peroxides to convert iodide to iodine,
M el-Saadani   +5 more
doaj   +1 more source

Ferroptosis: Mechanism and connections with cutaneous diseases

open access: yesFrontiers in Cell and Developmental Biology, 2023
Ferroptosis is a recognized novel form of programmed cell death pathway, featuring abnormalities in iron metabolism, SystemXc−/glutathione axis, and lipid peroxidation regulation.
Lihao Liu   +4 more
doaj   +1 more source

The interaction between ferroptosis and lipid metabolism in cancer

open access: yesSignal Transduction and Targeted Therapy, 2020
Ferroptosis is a new form of programmed cell death characterized by the accumulation of iron-dependent lethal lipid peroxides. Recent discoveries have focused on alterations that occur in lipid metabolism during ferroptosis and have provided intriguing ...
Dingshan Li, Yongsheng Li
semanticscholar   +1 more source

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]

open access: yes, 2008
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn   +30 more
core   +3 more sources

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review

open access: yesFrontiers in Physiology, 2019
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD) characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and biochemically different from known types of cell death. Ferroptosis plays a vital
Pengxu Lei, Tao Bai, Yuling Sun
doaj   +1 more source

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

open access: yesRedox Biology, 2019
The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is a key regulator of the cellular antioxidant response, controlling the expression of genes that counteract oxidative and electrophilic stresses.
M. Dodson   +2 more
semanticscholar   +1 more source

Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]

open access: yes, 2016
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo   +2 more
core   +2 more sources

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