Results 31 to 40 of about 831,459 (395)

Immunogenicity, protective efficacy, and non-replicative status of the HSV-2 vaccine candidate HSV529 in mice and guinea pigs. [PDF]

PLoS ONE, 2015
HSV-2 vaccine is needed to prevent genital disease, latent infection, and virus transmission. A replication-deficient mutant virus (dl5-29) has demonstrated promising efficacy in animal models of genital herpes.
Marie-Clotilde Bernard, Véronique Barban, Fabrine Pradezynski, Aymeric de Montfort, Robert Ryall, Catherine Caillet, Patricia Londono-Hayes   +6 more
doaj   +1 more source

Discovery of AZD3199, an inhaled ultralong acting β2 receptor agonist with rapid onset of action [PDF]

, 2014
A series of dibasic des-hydroxy β2 receptor agonists has been prepared and evaluated for potential as inhaled ultra-long acting bronchodilators. Determination of activities at the human β-adrenoreceptors demonstrated a series of highly potent and ...
Alcaraz L., Alikhani V., Anderson G. P., Austin R. P., Bao Y., Baur F., Bouyssou T., Cazzola M., Connolly S., Cooper A. E., Davies S. L., Deyrup M. D., Fuso L., Giles M. E., Green S. A, Kuna P., Matera M. G., Mortimer K. J., Patton J. S., Procopiou P. A., Procopiou P. A., Roig J., Stocks M. J., Tayab Z. R., Walker J. K. L., Walland A., White M. V.   +26 more
core   +2 more sources

Peculiarities of changes in a functional condition of pro-oxidant and antioxidant systems in guinea pigs’ lungs in experimental allergic alveolitis under the conditions of immobilization stress

Journal of Education, Health and Sport, 2017
We have analyzed the results of investigation of alterations in indices of pro-oxidant (conjugated diene and malondialdehyde) and antioxidant (superoxide dismutase, ceruloplasmin, catalase) systems in guinea pigs’ lungs in experimental allergic ...
Mykhailo Stepanovych Reheda, Marta Yevhenivna Kovalska, Mariana Ljubomurivna Baida   +2 more
doaj   +3 more sources

A FILTERABLE VIRUS PRESENT IN THE SUBMAXILLARY GLANDS OF GUINEA PIGS

Journal of Experimental Medicine, 1926
In the lesions of herpes simplex and similar conditions due to filterable viruses, cells are present which show characteristic alterations, particularly in the nucleus. The nucleus of these cells contains a mass which stains with acid dyes.
R. Cole, A. Kuttner
semanticscholar   +1 more source

Distribution and Excretion of TEGDMA in Guinea Pigs and Mice [PDF]

, 2001
The monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based dental materials. It was previously shown in vitro that TEGDMA was released into the adjacent biophase from such materials during the first days after placement.
A. Jewett, F.X. Reichl, Forst HT, G.W. Moes, H. Kreppel, J. Durner, K. Kehe, K.H. Kunzelmann, M.Y. Wang, R. Hickel, Reichl FX, Saygili G., U. Walther, W. Forth, W. Spahl, W.R. Hume   +15 more
core   +1 more source

Polymorphism and Tissue Expression Analysis of TYR and MC1R Genes in Guinea Pigs with Different Coat-Color Phenotypes

Shiyan dongwu yu bijiao yixue
Objective To explore the polymorphism of tyrosinase (TYR) and melanocortin 1 receptor (MC1R) genes and their mRNA expression levels in relation to coat-color phenotypes in guinea pigs, providing genetic markers for locating dominant traits in guinea pigs.
TANG Yingen, FENG Yaxian, ZHONG Min, WEI Zhen, WANG Lie, LIU Diwen   +5 more
doaj   +1 more source

Effects of soy isoflavone genistein on orthodontic tooth movement in guinea pigs

Dental Journal, 2016
Background: Osteoblast and osteoclast are the important factor in periodontal tissue remodeling for the orthodontic treatment success. Resorption process takes place in compression area by osteoclast and apposition in the tension area by osteoblast.
Sri Suparwitri, Pinandi Sri Pudyani, Sofia Mubarika Haryana, Dewi Agustina   +3 more
doaj   +1 more source

Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs [PDF]

, 2016
Given the present extensive co-circulation in pigs of Eurasian avian-like (EA) swine H1N1 and 2009 pandemic (pdm/09) H1N1 viruses, reassortment between them is highly plausible but largely uncharacterized.
A Krumbholz, AV Cauldwell, B Manz, C Chiapponi, C Scholtissek, E Starick, GF Rimmelzwaan, GJ Smith, H Liang, H Yang, H Zhou, H Zhu, IH Brown, J Liu, J Pu, JA Vazquez-Perez, JC De Jong, K Shinya, M Pensaert, M Wedde, MA Jhung, N Marshall, NA Gerloff, NM Bouvier, Q Liu, Q Liu, R Zell, RA Perera, RK Nelli, S Chutinimitkul, SJ Watson, T Watanabe, W Kong, W Ma, W Ma, WL Kong, WL Kong, X Qi, X Xiong, X Zhao, XC Yin, Y Abed, Y Kawaoka, YK Choi   +43 more
core   +1 more source

Increased Small Dense LDL and Decreased Paraoxonase Enzyme Activity Reveals Formation of an Atherogenic Risk in Streptozotocin-Induced Diabetic Guinea Pigs

Journal of Diabetes Research, 2013
This study aimed to investigate LDL subfraction distribution as well as serum cholesteryl ester transfer protein (CETP), lecithin-cholesterol acyltransferase (LCAT), and paraoxonase (PON1) activity in streptozotocin-induced diabetic guinea pigs ...
Mutay Aslan, Filiz Ozcan, Ertan Kucuksayan   +2 more
doaj   +1 more source

The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model [PDF]

, 2007
Background. Nosocomial transmission of tuberculosis remains an important public health problem. We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and ...
A. Gonzalez, A. R. Escombe, Balasubramanian, Beggs, Bhatia, C. A. Evans, C. Martinez, C. Noakes, C. Oeser, Caviedes, Cohn, Curtis, D. A. J. Moore, E. Ticona, Edlin, Elliott, Escombe, Gangadharam, Ikeda, J. S. Friedland, Katz, L. Caviedes, Luna-Herrera, M. Navincopa, Markowitz, Mastorides, Mills, Mitchison, Mitchison, Nardell, Nardell, Nunn, P. Sheen, Prabhakar, R. H. Gilman, Riley, RILEY, Riley, Schafer, Sultan, Xu   +40 more
core   +2 more sources