Development and validation of a quantitative PCR for the detection of Guinea worm (Dracunculus medinensis). [PDF]
PLoS Neglected Tropical Diseases, 2022 Dracunculus medinensis (Guinea worm) is a parasitic nematode that can cause the debilitating disease dracunculiasis (Guinea worm disease) in humans. The global Guinea Worm Eradication Program has led intervention and eradication efforts since the 1980s ...
Sarah M Coker +7 more
doaj +2 more sources
Community-based Guinea worm surveillance in Chad: Evaluating a system at the intersection of human and animal disease. [PDF]
PLoS Neglected Tropical Diseases, 2021 BackgroundGuinea worm is a debilitating parasitic infection targeted for eradication. Annual human cases have dropped from approximately 3,500,000 in 1986 to 54 in 2019.
Beth L Rubenstein +10 more
doaj +2 more sources
Quantifying conflict zones as a challenge to certification of Guinea worm eradication in Africa: a new analytical approach [PDF]
BMJ Open, 2021 Objectives To quantify conflict events and access across countries that remain to be certified free of transmission of Dracunculus medinensis (Guinea worm disease) or require postcertification surveillance as part of the Guinea Worm Eradication Programme
Louise A Kelly-Hope, David H Molyneux
doaj +2 more sources
Linked surveillance and genetic data uncovers programmatically relevant geographic scale of Guinea worm transmission in Chad. [PDF]
PLoS Neglected Tropical Diseases, 2021 BackgroundGuinea worm (Dracunculus medinensis) was detected in Chad in 2010 after a supposed ten-year absence, posing a challenge to the global eradication effort. Initiation of a village-based surveillance system in 2012 revealed a substantial number of
Jessica V Ribado +11 more
doaj +2 more sources
Assessment of the Chad guinea worm surveillance information system: A pivotal foundation for eradication. [PDF]
PLoS Neglected Tropical Diseases, 2021 BackgroundIn the absence of a vaccine or pharmacological treatment, prevention and control of Guinea worm disease is dependent on timely identification and containment of cases to interrupt transmission.
Saugat Karki +12 more
doaj +2 more sources
Dog screening as a novel complementary guinea worm disease control tool to mitigate persistence in Chad: A modeling study [PDF]
Parasite Epidemiology and Control, 2023 A free-roaming dog population remains one of the major public health problems in many developing countries. In this study, we investigated the potential impact of owned roaming and stray dogs on the persistence and possible eradication of Guinea worm ...
Mlyashimbi Helikumi, Steady Mushayabasa
doaj +2 more sources
Guinea worm in domestic dogs in Chad: A description and analysis of surveillance data. [PDF]
PLoS Neglected Tropical Diseases, 2020 After a ten-year absence of reported Guinea worm disease in Chad, human cases were rediscovered in 2010, and canine cases were first recorded in 2012. In response, active surveillance for Guinea worm in both humans and animals was re-initiated in 2012 ...
Sarah Anne J Guagliardo +8 more
doaj +2 more sources
Identifying correlates of Guinea worm (Dracunculus medinensis) infection in domestic dog populations. [PDF]
PLoS Neglected Tropical Diseases, 2020 Few human infectious diseases have been driven as close to eradication as dracunculiasis, caused by the Guinea worm parasite (Dracunculus medinensis).
Robert L Richards +8 more
doaj +2 more sources
Ecology of domestic dogs Canis familiaris as an emerging reservoir of Guinea worm Dracunculus medinensis infection. [PDF]
PLoS Neglected Tropical Diseases, 2020 Global eradication of human Guinea worm disease (dracunculiasis) has been set back by the emergence of infections in animals, particularly domestic dogs Canis familiaris. The ecology and epidemiology of this reservoir is unknown.
Robbie A McDonald +7 more
doaj +2 more sources
Guinea Worm Disease: A Neglected Diseases on the Verge of Eradication [PDF]
Tropical Medicine and Infectious Disease, 2022 Background: Dracunculiasis, also known as Guinea worm disease (GWD), is a neglected tropical disease (NTD) caused by a parasite (Dracunculus medinensis).
Carmen Pellegrino +20 more
doaj +2 more sources