Results 161 to 170 of about 5,054 (206)

Potential Blood Biomarkers Predicting Treatment Response in Psoriasis: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Clin Med
Villa-Gonzalez JM   +6 more
europepmc   +1 more source

Guselkumab for the treatment of psoriasis

open access: yesExpert Opinion on Biological Therapy, 2018
Psoriasis is a chronic immune mediated disease in which the interplay of T cells and keratinocytes seems to play a key role. In this context, the interleukin (IL)-23/IL-17 axis is currently considered to be crucial in the pathogenesis of psoriasis and the selective inhibition of IL-23 may be viewed as an improvement of treatments blocking both IL-23 ...
Anna Balato   +2 more
exaly   +10 more sources

Guselkumab for the treatment of palmoplantar pustulosis

Expert Opinion on Biological Therapy, 2020
Palmoplantar pustulosis, or pustulosis palmaris et plantaris (PPP), is a chronic, recurrent inflammatory skin disease that is sometimes unresponsive to conventional therapy. The anti-interleukin 23 antibody guselkumab is effective for treating PPP.This review details the current understanding of PPP and discusses why guselkumab may be effective ...
Masamoto Murakami
exaly   +3 more sources

Development and validation of immunoassays for monitoring of guselkumab and anti-guselkumab antibodies in patients with moderate-to-severe psoriasis [PDF]

open access: yesJournal of Pharmaceutical and Biomedical Analysis, 2020
Therapeutic drug monitoring, which is the measurement of drug concentrations in the blood, is a useful tool to guide clinical decision-making and treatment adjustments, on the condition that drug concentrations are correlated with treatment response. For
Ann Gils, Els Brouwers, Lynda Grine
exaly   +2 more sources

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